Accès ouvert
2026
article
OpenAlex
Hsueh‐Wen Hsueh, Ping‐Hao Yang, Ping‐Huei Tseng, Ti‐Yen Yeh et autres
Hereditary ATTR amyloidosis with polyneuropathy (ATTRv-PN) frequently presents with gastrointestinal autonomic dysfunction, but its underlying pathology remains unclear. We examined gastric mucosal amyloid deposition and innervation using conventional endoscopic biopsies in ATTRv-PN patients and a human TTR (hTTR A117S) knock-in mouse model. …
Accès ouvert
2026
article
OpenAlex
Hsueh‐Wen Hsueh, Ping‐Hao Yang, Ping‐Huei Tseng, Ti‐Yen Yeh et autres
Hereditary ATTR amyloidosis with polyneuropathy (ATTRv-PN) frequently presents with gastrointestinal autonomic dysfunction, but its underlying pathology remains unclear. We examined gastric mucosal amyloid deposition and innervation using conventional endoscopic biopsies in ATTRv-PN patients and a human TTR (hTTR A117S) knock-in mouse model. …
2026
article
OpenAlex
Hsueh‐Wen Hsueh, Ping‐Hao Yang, Ping-Huei Tseng, Ti‐Yen Yeh et autres
Backgrounds Hereditary ATTR amyloidosis with polyneuropathy (ATTRv-PN) frequently presents with gastrointestinal autonomic dysfunction, but its underlying pathology remains unclear.Methods We examined gastric mucosal amyloid deposition and innervation using conventional endoscopic biopsies in ATTRv-PN patients and a human TTR (hTTR A117S) knock-in mouse …
tw
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Tsai-Wei Ting, Chih‐Ning Cheng, Chieh‐Chang Chen, Ching-Hua Kuo
Gut microbiota has recently gained attention for its role in regulating multiple host pathways and contributing to disease developments. Fecal metabolomics using liquid chromatography-mass spectrometry (LC-MS) offers a promising approach to study gut microbial metabolites; however, it remains technically challenging due to …
tw
(code pays fourni par la source)