R-CHOP in B cell non-Hodgkin lymphoma: balancing anti-tumor efficacy and NK-cell functionality
Johanna Jansky, Hannah Breitung, Sylvia Zöphel, Laetitia Döngi et autres
Abstract Combining the anti-CD20 antibody rituximab with the chemotherapeutic drugs vincristine, doxorubicin, and cyclophosphamide plus the corticosteroid prednisone (R-CHOP) has been the standard first line-line therapy for many non-Hodgkin lymphomas including diffuse large B-cell lymphoma (DLBCL) for more than 20 years. Natural …
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bioRxiv (Cold Spring Harbor Laboratory)