Accès ouvert
2026
article
OpenAlex
Caitlin R. Rausch, Kayleigh Marx, Ying Jiang, Elias Jabbour et autres
Abstract Background Vincristine (VCR) is an essential component of combination chemotherapy for patients (pts) with acute lymphoblastic leukemia (ALL). VCR neurotoxicity (NTX) which can present as peripheral neuropathy, constipation, or ileus, is a well-known dose-limiting side effect. As pts with ALL are …
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Accès ouvert
2026
article
OpenAlex
Saliba Wehbe, Ramia Zakhour, Ray Hachem, Hiba Dagher et autres
Abstract Background Invasive aspergillosis (IA) remains the most common invasive mold infection in pediatric and adult patients with cancer or hematopoietic stem cell transplant (HCT), leading to substantial morbidity and mortality. Differences in IA presentation, diagnosis, management, and outcomes between children and …
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Accès ouvert
2026
article
OpenAlex
Bahgat Z Gerges, Joel Rosenblatt, Y Lan Truong, Ying Jiang et autres
Abstract Background Polymicrobial biofilms of bacteria and fungi frequently occur in chronic wounds and pose a significant barrier to healing. Polygalacturonic + caprylic acids (PG+CAP) and hypochlorous acid (HOCl) have been shown to be well tolerated yet potent antimicrobial agents for eradicating …
us
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Accès ouvert
2026
article
OpenAlex
Y Lan Truong, Joel Rosenblatt, Bahgat Z Gerges, Ying Jiang et autres
Abstract Background The prevalence of Central Line Associated Bloodstream Infections (CLABSIs) due to Candida species continues to increase, hence CVCs with improved antifungal activities are needed. The FDA recently cleared a new antimicrobial CVC containing Chlorhexidine (C), Minocycline (M) and Rifampin (R). …
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Accès ouvert
2026
article
OpenAlex
Y Lan Truong, Joel Rosenblatt, Bahgat Z Gerges, Ying Jiang et autres
Abstract Background Central Line Associated Bloodstream Infections (CLABSIs) have been designated “never events” hence CVCs with improved antibacterial activities are needed. The FDA recently cleared a new CVC containing Chlorhexidine (C), Minocycline (M) and Rifampin (R). This makes available a third antibiotic …
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