Accès ouvert
2026
article
OpenAlex
Stephanie A. Schultz, Yi Rao, L Liu, Beth L. Ostaszewski et autres
INTRODUCTION: Tau species lacking truncation of the N-terminal region, including plasma N-terminal tau fragment 1 (NT1), have been previously associated with cognitive decline, neurodegeneration, and tau pathology in late-onset sporadic Alzheimer's disease (AD). METHODS: Here, we examined cross-sectional and longitudinal plasma NT1 …
us, ar, gb, de, au
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Azadeh Feizpour, Pierrick Bourgeat, Vincent Doré, Dr James Doecke et autres
Abstract Background The agreement between plasma Aβ42/40 and Aβ‐PET is approximately 75%, with a large portion of discrepancies due to positive plasma with negative PET results. Questions remain about whether these reflect brain Aβ changes detectable in plasma before PET‐detectable. We aimed …
au, us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Chengjie Xiong, Jingqin Luo, David A. Wolk, Leslie M. Shaw et autres
Abstract Background Whereas longitudinal data are needed to pinpoint the exact age when individuals become positive for biomarkers of Alzheimer disease (AD), cross‐sectional data can be used to examine the typical age of biomarker positivity across groups. Using cross‐sectional data, we estimated …
us
(code pays fourni par la source)