Psoralen immunomodulation: In vitro macrophage reprogramming to enhance osseointegration of 3D-printed porous titanium scaffolds in osteoporosis
Jian Ji, Jijie Peng, Yilong Wu, Yue Meng et autres
Psoralen inhibits osteoclast activity and bone resorption while enhancing osteoblast activity and bone formation. However, its role in modulating macrophage polarization to enhance osteoblast function and scaffold osseointegration under osteoporotic conditions remains underexplored. We fabricated Voronoi-structured metal scaffolds by 3D printing and …
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International Journal of Bioprinting