Identification and Functional Characterization of the Axolotl ( Ambystoma mexicanum ) Tau Protein
Zachary Strickland, Benoit I. Giasson, Jada Lewis
BACKGROUND: Tauopathies are characterized by abnormal aggregation of tau that results in neuronal dysfunction and degeneration. Developing strategies to preserve existing neuronal function, prevent neurodegeneration, or restore lost neurons may have the most potential to combat human tauopathy; however, the adult human …
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Alzheimer s & Dementia