Functional and structural analysis of KK-LC-1-specific T cell receptors from patients with lung Cancer for immunotherapy
Yasunori Fukushima, Yizheng Wang, Yuki Yada-Makino, Hiroyasu Komuro et autres
Adoptive T-cell receptor (TCR)-engineered T cell therapy is a promising approach for cancer immunotherapy, particularly for cancer/testis antigens such as KK-LC-1. We evaluated four KK-LC-1 epitope-specific TCRs restricted by Human Leukocyte Antigen (HLA)-B*15:01, including three identified by our group and one previously …
jp (code pays fourni par la source)
0 citations
Cellular Immunology