Ryan Vethanayagam

Low-Density Lipoprotein Cholesterol Reduction with Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies in Women: A Systematic Review

Olivia Buttenham, Ryan Vethanayagam, Samuel L. Triemstra, Michael P. Heffernan

Background Cardiovascular disease remains the leading cause of mortality among women worldwide and accounts for approximately one-third of all deaths globally. Elevated low-density lipoprotein cholesterol (LDL-C) is a well-established, causal, and modifiable risk factor in the development of atherosclerotic cardiovascular disease (ASCVD). …

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Ceftaroline Use in Pediatric Patients: A Scoping Review

Ryan Vethanayagam, Connor Chan, Vinoj Kehelwathugoda, Kevin Meesters

This project contains the protocol and search strategy for a scoping review mapping systemic ceftaroline use in pediatric patients aged 0 to 18 years, including indications, dosing, pharmacokinetics/pharmacodynamics, microbiology, safety, and clinical outcomes.

Upfront comprehensive donor search overcomes the impact of poor search prognosis, irrespective of racial background

Fei Fang, Ryan Vethanayagam, Karen R. Sherwood, James H. Lan et autres

Abstract Introduction: Access to suitably matched donors remains a major barrier to allogeneic hematopoietic cell transplantation (HCT), particularly for non-White patients, who are underrepresented in global donor registries. Traditional donor search strategies vary in timing and resource intensity, often leading to delays …

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