Precision at Every Scale: Efficiency in AI-Driven De Novo Antibody Design
Kyesoo Cho, Jeonghyeon Gu, Daehyeon Gwak, S. W. Ham et autres
Abstract The precise de novo design of antibodies remains a therapeutic challenge. The AI platform, GaluxDesign, was evaluated in a high-efficiency Precision-Scale Workflow by synthesizing and testing only 50 full-length IgG candidates per epitope across eight distinct epitopes from six therapeutic targets. …
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bioRxiv (Cold Spring Harbor Laboratory)