Zhibing Qiu

Combined Left Ventricular Assist Device and Temporary Right Ventricular Assist Device for End- Stage Heart Failure of Different Etiologies: A Case Series and Analysis of Perioperative Management Strategies

Shengjie Ning, Junzhe Wang, Li Yin, Haoran Gan et autres

cn (code pays fourni par la source)

Early Experience of a Fully Magnetically Levitated Temporary Ventricular Assist Device in China: A Multicenter Single-Arm Study

Ping Li, Tingting Wu, I-Wen Wang, Wei Su et autres

Mechanical circulatory support (MCS) is an important option for patients unresponsive to medical therapy. This prospective, multicenter, single-arm study assessed the safety and efficacy of the newly developed MoyoAssist extracorporeal ventricular assist device (magAssist, Suzhou, China) in Chinese patients with cardiogenic shock …

hk, cn, us (code pays fourni par la source)

LIGHT: Learning Image-text Grounding for Hierarchical Tumor Localization and Subtype Classification in Multimodal Brain MRI

Zhibing Qiu, Yuxiao Liu, Jianrui Li, Lei Jin et autres

Accurate MRI-based brain tumor analysis requires not only tumor subtype classification but also localization at an anatomical granularity that is consistent with radiology reports. Most vision-only methods address localization and classification as separate label-prediction tasks, and therefore provide limited alignment with the …

cn (code pays fourni par la source)

Influencing Factors of Postoperative Mechanical Ventilation Weaning Outcomes in Acute Stanford Type A Aortic Dissection: A Single-Center Retrospective Study

Yifei Zhou, Shukun Wang, Wen Chen, Zhibing Qiu

Aims/Background Patients with acute Stanford type A aortic dissection (ATAAD) face particularly high risks of prolonged mechanical ventilation and weaning failure due to the combined effects of surgical trauma, systemic inflammation, and multi-organ involvement. However, current weaning predictors are primarily derived from …

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Safety and Efficacy of the Corheart 6 Left Ventricular Assist System

Zhibing Qiu, Xiaochun Song, Hongwei Shi, Xiaomin Zhang et autres

To assess the efficacy and safety of the Corheart 6 Left Ventricular Assist System (LVAS) in patients with end-stage heart failure. A retrospective cohort study was conducted at Nanjing First Hospital to evaluate the clinical outcomes of patients with end-stage heart failure …

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Huaier overcomes tumor-induced immunosuppression in colorectal cancer by activating MHC I and CD8+ T cells

Jiayu Chen, Yuxue Li, Qingyang Sun, Yaxian Wang et autres

BACKGROUND: Colorectal cancer (CRC) remains a leading cause of cancer-related mortality, primarily due to its immunosuppressive microenvironment that facilitates immune evasion and resistance to therapy. Although the traditional Chinese medicine Trametes robiniophila Murr (Huaier) has been shown to exert anti-tumor effects, its …

cn, hk, us (code pays fourni par la source)

Reoperation for the implantation of Corheart 6 biventricular assist devices due to severe right ventricular failure and aortic regurgitation following left ventricular assist device implantation

Yafeng Liu, Li Yin, Yiming Liu, Liqiong Xiao et autres

BACKGROUND: We present the case of a 68-year-old patient who underwent secondary thoracotomy, implantation of a continuous-flow ventricular assist device (VAD) in a biventricular configuration, and aortic valve replacement (AVR) 2 years after receiving a continuous-flow left ventricular assist device (LVAD) and …

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Ferroptosis-disulfidptosis-related CHMP6 is a clinico-immune target in colorectal cancer

Yifei Zhu, Huixia Huang, Jiayu Chen, Keji Chen et autres

BACKGROUND: Ferroptosis and disulfidptosis are newly discovered forms of regulated cell death that play critical roles in cancer progression, metabolism, and immune evasion. However, their interplay and combined influence on colorectal cancer (CRC) progression remain insufficiently understood. METHODS: We developed a ferroptosis-disulfidptosis-related …

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The modified heart team protocol facilitated the revascularization decision-making quality in complex coronary artery disease

Hanping Ma, Shen Lin, Xi Li, Yang Wang et autres

OBJECTIVES: A lack of standardization in heart team implementation potentially leads to suboptimal decision-making quality, and we previously established a modified heart team protocol to improve the decision-making quality. The present trial was to validate the effect of the modified heart team …

cn, us (code pays fourni par la source)

IKKα-STAT3-S727 axis: a novel mechanism in DOX-induced cardiomyopathy

Ganyi Chen, Yiwei Yao, Yafeng Liu, Ruoyu Zhang et autres

Doxorubicin (DOX) is an effective chemotherapeutic drug, but its use can lead to cardiomyopathy, which is the leading cause of mortality among cancer patients. Macrophages play a role in DOX-induced cardiomyopathy (DCM), but the mechanisms undlerlying this relationship remain unclear. This study …

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Targeting translocator protein protects against myocardial ischemia/reperfusion injury by alleviating mitochondrial dysfunction

Chenghao Wen, Yunfei Jiang, Wen Chen, Yueyue Xu et autres

Ischemic heart disease (IHD) remains a leading cause of mortalities worldwide, necessitating timely reperfusion to reduce acute mortality. Paradoxically, reperfusion can induce myocardial ischemia/reperfusion (I/R) injury, which is primarily characterized by mitochondrial dysfunction. Translocator protein (TSPO) participates in multiple cellular events; however, …

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Fecal microbiota transplantation for Parkinson's patients with constipation: A pilot clinical trial

Zhibing Qiu, Huilu Zhang, Cong Shen, Jie Liu et autres

Abstract Background Gut dysbacteriosis is closely related to Parkinson's disease. Fecal microbiota transplantation (FMT) has been proposed as an effective way to reconstruct gut microbiota. We launched a clinical study to examine the safety and efficacy of FMT for Parkinson’s disease.Methods Five …

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