Accès ouvert
2026
article
OpenAlex
Yozlem Ali Kobakova, Angelina Georgieva Kirkova-Bogdanova, Maria Stamova Vakrilova Becheva, Niya Emilova Semerdzhieva et autres
This retrospective study evaluates the etiological spectrum, antimicrobial resistance patterns, and pharmacokinetic/pharmacodynamic (PK/PD) challenges in patients with sepsis treated at the Clinic of Internal Diseases, UMBALSM “N. I. Pirogov,” Sofia. A total of 760 blood cultures collected over a 24-month period (12 …
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Accès ouvert
2026
article
OpenAlex
V. Marinov, Konstantin Ivanov Kostov, Yozlem Ali Kobakova, Angelina Georgieva Kirkova-Bogdanova et autres
Gastric leak after laparoscopic sleeve gastrectomy (SG) is a rare but life-threatening complication requiring timely diagnosis and coordinated multidisciplinary management. Therapeutic options include conservative treatment, percutaneous drainage, endoscopic interventions, and surgical revision. This case describes an early gastric leak successfully managed through …
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Accès ouvert
2026
article
OpenAlex
Maria Hristova Savcheva, Angelina Georgieva Kirkova-Bogdanova, Maria Sevdelinova Chaneva, Maria Stamova Vakrilova Becheva et autres
Transfusion medicine has undergone a long historical evolution—from early attempts at animal-to-animal transfusion through animal-to-human procedures to successful human-to-human transfusions following the discovery of blood groups. Today, it represents an independent field of medical science that supports key clinical specialties, such as …
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Accès ouvert
2025
article
OpenAlex
Maria Hristova Savcheva, Maria Stamova Vakrilova Becheva, Yozlem Ali Kobakova, Maria Georgieva Moneva-Sakelarieva et autres
Hemolytic disease of the newborn is a condition caused by maternal alloimmunization against fetal red blood cell antigens. Transplacental hemorrhage, for example, can provoke an immune response in the mother. As a result, IgG-class antibodies directed against fetal erythrocyte antigens are synthesized. …
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