Kamali Murugadoss

Pharmacogenetic Predictors of Chemotherapy Treatment-Related Toxicities in Paediatric and Adolescent Acute Lymphoblastic Leukemia: A Systematic Review, Meta-Analysis and Literature-Based Candidate Prioritization

Santenna Chenchula, Suresh Kumar Srinivasamurthy, Vinnyfred Vincent, Himani Thakkar et autres

Background: Childhood and adolescent acute lymphoblastic leukemia (ALL) survival outcomes have improved significantly, but treatment-related toxicities (TRTs) remain a major concern affecting dose intensity and quality of life. Germline pharmacogenetic variations contribute to inter-individual differences in chemotherapy response, yet consistent replication of …

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Molecular and Pharmacogenetic Marker Evaluation in Relation to the Toxicity and Clinical Response of Acute Lymphoblastic Leukemia Treatment in Indian Children (MPGx-INDALL): Protocol for a Prospective Observational Cohort Study

Swetambri Sharma, Shuvadeep Ganguly, Kamali Murugadoss, Smita Kayal et autres

Background: Understanding interindividual variability in treatment response and toxicity is essential for optimizing outcomes in pediatric acute lymphoblastic leukemia (ALL). Molecular and pharmacogenetic markers hold promise in predicting treatment efficacy and adverse effects, particularly in genetically diverse populations. This protocol outlines the …

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Molecular and Pharmacogenetic marker evaluation in relation to the toxicity and clinical response of acute lymphoblastic leukemia treatment in Indian children (MPGx-INDALL): A Prospective observational cohort study protocol (Preprint)

Swetambri Sharma, Shuvadeep Ganguly, Kamali Murugadoss, Smita Kayal et autres

BACKGROUND Understanding inter-individual variability in treatment response and toxicity is essential for optimizing outcomes in pediatric acute lymphoblastic leukemia (ALL). Molecular and pharmacogenetic markers hold promise in predicting treatment efficacy and adverse effects, particularly in genetically diverse populations. This protocol outlines the …

Burden of biocide resistance among multidrug-resistant bacteria isolated from various clinical specimens in a tertiary care hospital

Ramit Kundu, Kamali Murugadoss, Meerabai Manoharan, Jharna Mandal

BACKGROUND: Most studies on biocide resistance and its genetic determinants arise from environmental or food-borne microbial isolates and only a few from clinically relevant isolates. OBJECTIVES: This study determines the proportion of biocide resistance against five commonly used biocides and detects biocide …

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