Muhammad Ipoola Adeyemi

Immunological Determinants of Oncogenic Virus-Driven Cancers in Africa: Mechanisms, Co-Infections and Public Health Challenges

Victor Ayodele Aliyu, Olalekan Chris Akinsulie, Babatunde Ibrahim Olowu, Ibrahim Idris et autres

Oncogenic viruses contribute to approximately 20% of human cancers globally, with their impact falling disproportionately on populations in Sub-Saharan Africa. In this region, cervical cancer, hepatocellular carcinoma, endemic Burkitt lymphoma, and Kaposi sarcoma represent major causes of cancer-related morbidity and mortality, driven …

us, Nigéria, gb, no (code pays fourni par la source)

Immunological Determinants of Oncogenic Virus Driven Cancers in Africa: Mechanisms, Co-Infections and Public Health Challenges

Victor Ayodele Aliyu, Olalekan Chris Akinsulie, Babatunde Ibrahim Olowu, Ibrahim Idris et autres

Oncogenic viruses contribute to approximately 15–20% of human cancers globally, with their impact falling disproportionately on populations in Sub-Saharan Africa. In this region, cervical cancer, hepatocellular carcinoma, endemic Burkitt lymphoma, and Kaposi sarcoma represent major causes of cancer-related morbidity and mortality, driven …

Advances in Antibody Engineering for Therapeutic Development: Molecular Strategies and Clinical Applications

Olalekan Chris Akinsulie, Sinem Ulusan, Ibrahim Idris, Sammuel Shahzad et autres

Antibodies are highly specialized glycoproteins produced by B cells in response to antigenic stimulation. They are a major component of the adaptive immune system and play a key role in host defenses by detecting, neutralizing, and eliminating foreign antigens. Over the years, …

us, Nigéria, gb, no (code pays fourni par la source)

Mechanisms and Therapeutic Potential of Nutritional Immunity

Charles Egede Ugwu, Olalekan Chris Akinsulie, Toyin Florence Ayandokun, Favour Akinfemi Ajibade et autres

Nutritional immunity is a major facet of host defense, wherein the host immune system strategically limits pathogen access to critical nutrients, including iron, zinc, vitamins, lipids, and amino acids, to repress microbial proliferation and virulence. This review provides a comprehensive synthesis of …

Nigéria, us, gb, no (code pays fourni par la source)

Mechanisms and Therapeutic Potential of Nutritional Immunity

Charles Egede Ugwu, Olalekan Chris Akinsulie, Toyin Florence Ayandokun, Favour Akinfemi Ajibade et autres

Nutritional immunity is a major facet of host defense, wherein the host immune system strategically limits pathogen access to critical nutrients, including iron, zinc, vitamins, lipids, and amino acids, to repress microbial proliferation and virulence. This review provides a comprehensive synthesis of …

Nigéria, us, gb (code pays fourni par la source)

Computational immunogenomics: Leveraging AI to uncover novel biomarkers for disease diagnosis and therapy

Ogochukwu Peace Chinedu-Nzereogu, Victory Olamide Olorunfemi, Joseph Olamide Osifeso, Tobi John Oluwayemi et autres

In a groundbreaking fusion of Artificial Intelligence (AI) and immunogenomics, the quest for precision medicine is being redefined, unlocking novel biomarkers that revolutionize disease diagnosis and therapy. This review unveils how AI harnesses the power of multi-omics data genomics, transcriptomics, and proteomics …

Neoantigen-driven cancer vaccines: Revolutionizing precision oncology through personalized immunotherapy

Victor Chinedu Nzereogu, Christopher Chukwujindu Opoh, Tobi John Oluwayemi, Muhammad Ipoola Adeyemi et autres

Neoantigen-driven cancer vaccines have emerged as a transformative approach in precision oncology, harnessing tumor-specific mutations to elicit robust, tailored immune responses. This review focuses on neoantigen identification, vaccine platforms, clinical applications, and challenges. Leveraging next-generation sequencing (NGS) and bioinformatics, vaccines target neoantigens …

Nigéria, no (code pays fourni par la source)