Enhancing Type 1 Diabetes Polygenic Risk Prediction Through Neural Networks and Entropy-Derived Insights
Antonio Nadal-Martínez, Guillermo Pérez-Solero, Sandra Ferreiro López, Jorge Blom-Dahl et autres
Type 1 diabetes (T1D) is an autoimmune disease with a strong genetic component (~70% heritability). Early identification of individuals at risk is crucial for early intervention or risk assessment. Although polygenic risk scores (PRS) have shown promise in risk assessment, most current …
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