Mary Bortoluzzi

Amino Oxidase Hard Protein Corona with Metabolic-Triggered Intracellular Biocatalysis

Federica Tonolo, Mary Bortoluzzi, Graziano Rilievo, Alessandro Cecconello et autres

A hard protein corona was engineered onto tannic acid-modified magnetic nanoparticles (SAMN@TA), a magnetic and luminescent core–shell nano-carrier, using bovine serum amine oxidase (BSAO), an enzyme catalyzing the oxidation of polyamines and producing the corresponding aldehydes and hydrogen peroxide. The absorption and …

Report progetto Young Resercher PNRR_Federica Tonolo

Federica Tonolo, Sara Khazzar, Marta Castrica, Mucignat Greta et autres

This study was funded by the European Union - NextGenerationEU, in the framework of the iNEST - Interconnected Nord-Est Innovation Ecosystem (PNRR M4C211.5, iNEST ECS00000043, CUP C43C22000340006) The views and opinions expressed are solely those of the authors and do not necessarily …

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Report progetto Young Resercher PNRR_Federica Tonolo

Federica Tonolo, Sara Khazzar, Marta Castrica, Mucignat Greta et autres

This study was funded by the European Union - NextGenerationEU, in the framework of the iNEST - Interconnected Nord-Est Innovation Ecosystem (PNRR M4C211.5, iNEST ECS00000043, CUP C43C22000340006) The views and opinions expressed are solely those of the authors and do not necessarily …

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DNA‐Iron Oxide Templated Multifunctional Nanocarbon Networks

Graziano Rilievo, Haosen Miao, Aura Cencini, Mary Bortoluzzi et autres

The assembly of hybrid nanocomposites often leads to the emergence of new properties. For example, DNA‐scaffolded colloidal gold can exhibit chiroplasmonic signals, while nanocomposite‐integrated carbon nanotubes display gating properties. Here, we investigate the application of core–shell iron oxide‐DNA nanoparticles as a universal …

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Plasmonic Nano-bolas Hunt DNA Targets

Aura Cencini, Graziano Rilievo, Mirco Zerbetto, Mary Bortoluzzi et autres

We present the design principles and assembly route for a reconfigurable DNA-scaffolded nanomachine comprising a fluorophore and two gold nanoparticles (AuNPs) operated by DNA strand displacement. The mechanism confines the fluorophore in the proximity of one or simultaneously two DNA-tethered 15 nm …

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Nanohybridization as a Route to a Water-Friendly Therapeutic Tool for Rescuing Misfolded Proteins

Mary Bortoluzzi, Aura Cencini, Lavinia Rutigliano, Graziano Rilievo et autres

High Resolution Image Download MS PowerPoint Slide Misfolded proteins cause several threatening pathologies, ranging from Alzheimer’s disease to cystic fibrosis. Although several protein folding correctors were tested, their delivery is usually inadequate. Here, via a self-assembly wet reaction, colloidal γ-Fe 2 O …

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Antimicrobial and Anti-Inflammatory Bioactive Peptides: Their Role in Potential Therapeutic Applications for Periodontitis—A Narrative Review

Federica Tonolo, Renata Cristina Lima Silva, Mary Bortoluzzi, Raquel Mantuaneli Scarel‐Caminaga et autres

Bioactive peptides have garnered increasing interest in recent years due to their potential applications in the medical field, for example, as promising adjuvant therapeutic agents to modulate the host immune response and counteract microbial dysbiosis in chronic pathologies. Primarily derived from protein …

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Colloidal Hollandite Holey Rods Produced by Presynthetic Nanohybridization

Ilenia M. D’Angeli, Graziano Rilievo, Simone Molinari, Anna Barbaro et autres

nanoparticles were self-assembled and investigated as precursors for a KFTO material. Presynthetic nanohybridization is a way to organize the components, with the caveat that the mere nanomaterial combination cannot grant a high degree of control due to their general susceptibility to aggregation, …

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A DNA-Based Plasmonic Nano-Ruler

Aura Cencini, Mary Bortoluzzi, Graziano Rilievo, Federica Tonolo et autres

DNA is an exceptional building block for the fabrication of dynamic supramolecular systems with switchable geometries. Here, a self-assembled, tunable plasmonic-fluorescent nanostructure was developed. A precise sliding motion mechanism was operated through the control of strand displacement reactions, shifting two single-strand DNA …

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A DNA-Based Plasmonic Nano-Ruler

Aura Cencini, Mary Bortoluzzi, Graziano Rilievo, Federica Tonolo et autres

DNA is an exceptional building block for the fabrication of dynamic supramolecular systems with chemically switchable geometries. Here, a self-assembled, fine-tunable plas-monic-fluorescent ruler was developed. A precise sliding motion mechanism was operated through the strict control of strand displacement reactions, shifting two …

it (code pays fourni par la source)