Prasad Nithianandam

Liquid Lung Rest During Extracorporeal Life Support in a Neonatal Porcine Model of Acute Lung Injury

David Blauvelt, Anne Hesek, Michael Golecki, Prasad Nithianandam et autres

In patients with severe lung injury, extracorporeal life support (ECLS) enables lung rest, but the optimal strategy is unknown. This study compared liquid lung rest (LLR) versus standard gas rest ventilation in a porcine model of acute lung injury supported by ECLS. …

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A bioabsorbable adhesive wrap for sutureless arterial repair: Initial development and preclinical testing in a rat model

Prasad Nithianandam, Anne Hesek, Makana Steinmetz, Jackson D. Mills et autres

BACKGROUND: Traumatic arterial injuries are life-threatening if not surgically repaired. However, traditional suture repair can be complex, skill-dependent, time-consuming, and result in complications such as bleeding, aneurysm, occlusion, and stenosis. We present a novel bioabsorbable adhesive wrap that seals arterial defects after …

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A silicon membrane microfluidic oxygenator for use as an artificial placenta with minimal anticoagulation

David Blauvelt, Nicholas C. Higgins, Anne Hesek, Bianca N. De et autres

Extreme prematurity carries a high burden of morbidity and mortality. The artificial placenta is an emerging therapy that has the potential to improve outcomes in these patients. However, current devices in development are limited by inadequate hemocompatibility, a major barrier to the …

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1249: PERFLUOROCARBON LIQUID LUNG REST IMPROVES COMPLIANCE IN A SWINE MODEL OF EXTRACORPOREAL LIFE SUPPORT

David Blauvelt, Anne Hesek, Prasad Nithianandam, Michael Golecki et autres

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