Michele Tiberi

Structural basis of Nuclear Factor 1-X DNA recognition provides prototypic insight into the NFI family

Michele Tiberi, Michela Lapi, Louise J. Gourlay, Antonio Chaves-Sanjuán et autres

Nuclear Factor I (NFI) proteins are involved in adenovirus DNA replication and regulate gene transcription, stem cell proliferation, and differentiation. They play key roles in development, cancer, and congenital disorders. Within the NFI family, NFI-X is critical for neural stem cell biology, …

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Structural bases for Nuclear Factor 1-X activation and DNA recognition. Prototypic insight into the NFI transcription factor family

Michele Tiberi, Michela Lapi, Louise J. Gourlay, Antonio Chaves-Sanjuán et autres

ABSTRACT Nuclear Factor I (NFI) proteins were first identified in adenovirus DNA replication and later as regulators of gene transcription, stem cell proliferation, and differentiation. They play key roles in development, cancer and congenital disorders. Within the NFI family, NFI-X is critical …

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NF-Y acts as a molecular platform to guide the binding of the ER stress response factor to the ER-stress elements ERSE and ERSE II. A case of molecular 'asymmetric symmetry'

Michele Tiberi, Antonio Chaves-Sanjuán, Roberto Mantovani, Lorenzo Sassi et autres