Development of a Synthetic Platform for Ent‐Pimaranes Reveals their Potential as Novel Non‐Redox Active Ferroptosis Inhibitors
Immanuel Plangger, Alex Mühlsteiger, Julia Maria Berger, Julian Maximilian Feilner et autres
We present a comprehensive account on the evolution of a synthetic platform for a subfamily of ent-pimaranes. For the most complex member, norflickinflimiod C, five distinct strategies relying on either cationic or radical polyene cyclizations to construct the requisite tricyclic carbon scaffold …
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Chemistry - A European Journal