Hayam A. Alwabsi

Design, synthesis and biological evaluation of hydroxybenzothiazole-linked benzothiazole/benzoxazole conjugates as potent dual α-amylase and α-glucosidase inhibitors

Rafaqat Hussain, Hina Sarfraz, Umair Khurshid, Noor Alqurashi et autres

pk, sa (code pays fourni par la source)

Revolutionizing the potential of laccase from Bacillus paralicheniformis as an eco-friendly solution to reduce polychlorinated dibenzofurans contamination through integrated computational approach

Muhammad Naveed, Ayesha Saleem, Tariq Aziz, Urooj Rasheed et autres

pk, gr, sa (code pays fourni par la source)

Structure-guided optimization of N-(5-((2-oxopropyl) thio)-1,3,4-thiadiazol-2-yl) propionamide frameworks as potent SARS-CoV-2 Mpro inhibitor for treating coronavirus disease

Maher S. Alwethaynani, Reem Nabil Hassan, Rafaqat Hussain, Hina Sarfraz et autres

sa, cn, hk, pk, us (code pays fourni par la source)

A sustainable thiosemicarbazide-functionalized cotton biocatalyst for horseradish peroxidase immobilization: enhanced stability, reusability, and methylene blue degradation

Abdullah N. Alotaibi, Reda M. El‐Shishtawy, Ibrahim O. Althobaiti, Musab M. Aldhahri et autres

sa, ye (code pays fourni par la source)

Structure activity relationship-guided scaffold hopping for identification of novel thiadiazole derivatives as potent SARS-CoV-2 Mpro inhibitors

Maher S. Alwethaynani, Khaled Alzhrani, Hina Sarfraz, Tahir Ali Chohan et autres

Abstract The ongoing COVID-19 pandemic has presented enormous challenges to worldwide healthcare systems, and effective therapeutic strategies must accompany mass vaccination efforts. In this context, Mpro (the main protease of SARS-CoV-2) is arguably one of the most promising molecular targets for antiviral …

sa, pk (code pays fourni par la source)

Decoding the catalytic potential of a Cycloclasticus zancles ring-hydroxylating dioxygenase through computational analysis for enhanced PAH biodegradation

Muhammad Naveed, Ahmad Raza, Ahiba Adil, Abubakar Majeed et autres

pk, sa (code pays fourni par la source)

Synergistic Cu-MOF/graphene oxide/polycaprolactone hybrid architecture for laccase immobilization and bioremediation of bisphenol A

Abdullah N. Alotaibi, Rawan Altalhi, Abdullah Al-Dakhil, Hayam A. Alwabsi et autres

sa (code pays fourni par la source)

Elucidating the biodegradation potential of Nudix hydrolase from Bacillus paranthracis via different approaches

Muhammad Huzaifa Naveed, Nimra Hanif, Minahil Zahid, Muhammad Asjad Haseeb et autres

MBBL1 was investigated using in silico approaches. Polyfluoroalkyl substances (PFAS) are persistent environmental contaminants associated with serious health and ecological risks because of their stable chemical nature and strong resistance to breakdown. The enzyme sequence was retrieved from NCBI (Accession No. MFQ6175622.1), …

pk, sa (code pays fourni par la source)

In silico evaluation of protocatechuate 4,5-dioxygenase for environmental detoxification of persistent organic pollutants

Muhammad Naveed, Maryum Rasheed, Maida Salah Ud Din, Minahil Zahid et autres

pk, sa (code pays fourni par la source)

Immobilization of Bacillus-derived protease onto carboxymethyl chitosan aerogel: A bioactive platform for bacterial inactivation, skin cancer therapy, and accelerated wound healing

Hayam A. Alwabsi, Mody Albalawi

sa (code pays fourni par la source)

Optimization of 1-(Difluoromethyl)-6-(1H2 Imidazol-5-yl) Imidazo[1,5-a] Pyrazin-8(7H)-One Frameworks as Promising Cholinesterase Inhibitors for Treating Alzheimer’s Disease

Hanan M. Alharbi, Nawal Al‐Hoshani, Hina Sarfraz, Abubakar Sadiq Bello et autres

Acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE) inhibitors are used to increase acetylcholine levels in current symptomatic treatments for Alzheimer’s disease (AD), which is still the most common neurodegenerative illness. Through the synthesis and thorough assessment of a novel series of Imidazo-pyrazinone derivatives (8a–8l), …

sa, hk, Nigéria, us, pk (code pays fourni par la source)

Exploring the biocatalytic potential of Amycolatopsis japonica DyP in degrading plasticizer and phenolic-derived xenobiotic compounds

Muhammad Naveed, Ayesha Saleem, Tariq A. Aziz, Sadia Jabeen et autres

pk, gr, Madagascar, sa (code pays fourni par la source)