Abtin Ghasempour

MicroRNA-181a in acute lymphoblastic leukemia: expression pattern, target genes and its potential as a biomarker

Mohammad Jahanpanah, Abtin Ghasempour, Diana Mokhtari, Shirin Eshghi et autres

The exact etiology of Acute Lymphoblastic Leukemia (ALL) is not yet fully understood. Inherited genetic abnormalities and exposure to environmental risk factors are implicated in pathogenesis of ALL patients. Over the past two decades, epigenetic factors like microRNAs (miRs) have been in …

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Autophagy and Reactive Oxygen Species in Megakaryopoiesis and Platelet Production

Abbas Khosravi, Abtin Ghasempour, Mostafa Paridar, Pargol Mashati et autres

Megakaryocytes (MKs), which are differentiated from megakaryocytic–erythrocytic progenitors, generate platelets (PLTs) by expanding and branching their cellular fragments under the influence of cytokines and intercellular mechanisms such as autophagy and release of reactive oxygen species (ROS) in the bone marrow. Autophagy is …

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Long-Term Outcomes of Non-Total Body Irradiation Hematopoietic Stem Cell Transplantation in Pediatric Secondary Malignancies: Experience from a Single Center

Leila Jafari, Maryam Behfar, Shadi Khalili, Nadia Alipour et autres

Natural killer cell-based therapies in neuroblastoma

Abtin Ghasempour, Rashin Mohseni, Pouya Mahdavi Sharif, Amir Ali Hamidieh

Neuroblastoma (NB) is the most common extracranial solid tumor of childhood forming around 15 % of all pediatric tumors. Despite advances in the treatment of NB, high-risk patients still face a grave prognosis. Adoptive cell therapies based on NK cells are becoming …

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