ACBP/DBI neutralization for the experimental treatment of fatty liver disease
Omar Motiño, Flavia Lambertucci, Adrien Joseph, Sylvère Durand et autres
Abstract Acyl-CoA binding protein (ACBP), also known as diazepam-binding inhibitor (DBI), is an extracellular checkpoint of autophagy. Here, we report that patients with histologically confirmed metabolic-associated steatohepatitis (MASH) or liver fibrosis exhibit elevated levels of circulating ACBP/DBI protein as compared to non-affected …
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