Saidun Fiddaroini

Characterization and Immunogenicity of Thyroid Stimulating Hormone (TSH) Isolated from Neonatal Umbilical Cord Serum

Almas Dwi Khairana, Saidun Fiddaroini, Devi Ramadani, Muhammad Fikri Nur et autres

Congenital hypothyroidism (CH) is among the most prevalent and preventable causes of intellectual disability in neonates worldwide, with thyroid-stimulating hormone (TSH) serving as the primary biochemical screening biomarker. In Indonesia, limited availability of locally produced anti-TSH antibodies restricts the scalability of neonatal …

Structural Characterization and Immunogenic Evaluation of a 50 kDa Thyroid Peroxidase Fraction Isolated from Hypothyroid Patient Serum

Devi Ramadani, Aulanni'am Aulanni'am, Muh Fikry Baharuddin, Almas Dwi Khairana et autres

Thyroid peroxidase (TPO) is a key enzyme involved in thyroid hormone biosynthesis and one of the major autoantigens in autoimmune thyroid disease. However, studies investigating immunoreactive serum-derived TPO-related protein fractions remain limited. This study aimed to isolate an approximately 50 kDa immunoreactive …

Concentration-dependent green synthesis of ZnO nanoparticles using Physalis angulata Linn. leaf extract: Structural evolution, cytocompatibility, and anti-Streptococcus mutans activity

Delvi Fitriani, Saidun Fiddaroini, Nindyanne Fadilla Siswiansari, Ricky Alexsandro et autres

Dental caries remains a major global oral health problem primarily associated with the biofilm-forming bacterium Streptococcus mutans . Conventional antimicrobial agents often exhibit limited biofilm penetration and may induce resistance, highlighting the need for sustainable nanomaterial-based alternatives with enhanced antibacterial efficacy and …

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Preparation of Carrageenan/Chitosan/Curcumin Hydrogel Films: Physicochemical Characterization and In Vitro Evaluation as a Promising Diabetic Wound Dressing

Sry Agustina, Saidun Fiddaroini, Ahmad Luthfi Fahmi, Ruslan et autres

Wound dressings with their physical characteristics that can maintain moisture and their active content which possesses antibacterial and antioxidant properties, represent a crucial solution in addressing the delayed healing of diabetic wounds. For this purpose, in this work we prepared hydrogel films …

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Sustainable honey-mediated synthesis of oligochitosan-functionalized Ca(OH)₂ nanoparticles with enhanced antibacterial and biocompatible properties

Saidun Fiddaroini, Ardini Nurul Janah, Budi Mulyati, Ahmad Luthfi Fahmi et autres

• Honey-assisted green synthesis enables controlled formation of Ca(OH)₂ nanoparticles • Oligochitosan functionalization improves stability and surface bioactivity • Nanocomposites show enhanced antibacterial activity against Gram+ and Gram− bacteria • Molecular docking reveals multi-target interactions with bacterial proteins • Oligochitosan coating reduces …

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Surfactant-modified ZnO NPs enhance the corrosion barrier performance of PLA coatings on AA2024-T3 aluminum alloy

Budi Mulyati, Salma Nur Aisyah, Saidun Fiddaroini, Masruroh et autres

This work reported the fabrication of ZnO nanoparticles, which were then modified using surfactants to enhance the anticorrosion performance of polylactic acid (PLA) coatings on AA2024-T3 aluminum alloy. Surfactant-modified ZnO nanoparticles were synthesized under alkaline conditions via a precipitation method using cetyltrimethylammonium …

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Red amaranth betacyanin–incorporated Cs/PVA colorimetric films as smart sensors for real-time fish freshness monitoring

Alfianita Nuril Hidayaty, Saidun Fiddaroini, Ahmad Luthfi Fahmi, Dea Luthfianti Maharani et autres

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Optimization and Stability Assessment of Chitosan/PVA Smart Sensor Films Incorporated with Roselle Anthocyanins for Real-Time Visual Monitoring of Chicken and Shrimp Freshness under Different Storage Conditions

Alfianita Nuril Hidayaty, Saidun Fiddaroini, Ahmad Luthfi Fahmi, Qonitah Fardiyah et autres

The development of intelligent packaging systems has become a promising approach to ensure food safety and quality by enabling real-time freshness monitoring. In this study, chitosan/polyvinyl alcohol (Cs/PVA)-based smart sensor films incorporated with roselle (Hibiscus sabdariffa L.) anthocyanins were fabricated and optimized …

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Chitosan–PVA composite films incorporated with roselle anthocyanins: Colorimetric smart sensor for real-time monitoring of meat and seafood freshness

Alfianita Nuril Hidayaty, Saidun Fiddaroini, Ahmad Luthfi Fahmi, Stephani Rebecca Amabel Siahaan et autres

Ensuring freshness in perishable foods like meat and seafood is vital for food safety. This study developed a biodegradable colorimetric film from chitosan–polyvinyl alcohol (Cs/PVA) infused with roselle anthocyanin extract (CPAR) to monitor spoilage. Among variants, CPAR-5 (5 mL extract) showed the …

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Propolis and Hydroxyapatite Combination for Dentin Repair: Bioactivity, Target Prediction, and SAR Analysis

Chandra Sari Kurniawati, Saidun Fiddaroini, Retno Rahayu, Ira Widjiastuti

Preserving dental pulp vitality remains a critical challenge in restorative dentistry, particularly when managing deep carious lesions with potential pulpal exposure. In this study, a biofunctional approach is introduced by combining propolis, a natural resinous compound rich in bioactive flavonoids, with hydroxyapatite …

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Honey-mediated green synthesis and systematic optimization of Ni(OH)₂ nanoparticles with oligochitosan surface modification: Structural characterization, enhanced stability, and antibacterial biocompatibility

Saidun Fiddaroini, Berlian Zetta Batari, Budi Mulyati, Ahmad Luthfi Fahmi et autres

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PLA/ZnO nanocomposites with 0.05 % w/v ZnO enhanced long-term corrosion inhibition of low carbon steel

Budi Mulyati, Femiana Gapsari, Saidun Fiddaroini, Masruroh Masruroh et autres

The development of eco-friendly and high-performance corrosion inhibitors is crucial to preventing the long-term degradation of low-carbon steel (LCS) in aggressive environments. Conventional inhibitors often suffer from toxicity and limited durability, prompting the need for sustainable alternatives. In this study, polylactic acid …

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