Aya H. Rohiem

Protection by Vitis vinifera L. Against Cisplatin-Induced Testicular Injury: Oxidative Stress, Inflammation, and Ferroptosis

Salman A. A. Mohammed, ‏Hebatallah M. Saad, Kariman A. Esmail, Duaa Eliwa et autres

Background/Objectives: Testicular toxicity is one of the most important chemotherapeutic adverse effects of Cisplatin (Cisp), which restricts its use and effectiveness. This study investigated the preventive effects of Vitis vinifera L. extract on Cisp-induced testicular injury in rats. Methods: Forty adult albino …

sa, Égypte (code pays fourni par la source)

Deciphering the Role of NLRP-3/Caspase-1/GSDMD Pyroptotic Signal, miR-675-5p, and miR-1247-5p in Mitigation of Neurobehavioral and Neuropathological Alterations in Rotenone-Induced Striatal Neurodegeneration by Vitex agnus-castus Leaf Extract and/or Pramipexole in Male Rats

‏Hebatallah M. Saad, Kariman A. Esmail, Duaa Eliwa, Neveen R. Ashoura et autres

Rotenone (ROT ) exposure causes behavioral and motor abnormalities, including bradykinesia, catalepsy, and unsteady gait, as in Parkinsonism. Vitex agnus-castus (Vitex A-C) has been extensively utilized in the management of various female ailments besides its role as an agonist for D2 dopaminergic …

Égypte (code pays fourni par la source)

Ameliorative Impacts of Neem Leaf Powder on Cadmium Toxicity in Nile Tilapia: Growth Performance, Haemato-Biochemical, Oxidative and Pathological Insights

Heba Osama Saad, Riad H. Khalil, Asmaa A. Aboushouk, Adel Hassan Saad et autres

Our research sought to clarify the impact of Neem Leaf Powder (NP) as a feed supplement in reducing the harmful effects of CdCl2 toxicity in Nile tilapia. Acclimated 360 fish were allocated randomly into 4 treatments with 3 repetitions in each group, …

Égypte, cn (code pays fourni par la source)

Neuroprotective Activities of Nigella sativa Ethanolic Extract and Telmisartan Against Fipronil-Induced Neurotoxicity in Rats via Regulation of Apoptosis, Endosomal Micro-autophagy, and miRNA-137-5p

Aya H. Rohiem, ‏Hebatallah M. Saad, Duaa Eliwa, Neveen R. Ashoura et autres

The purpose of our study was to investigate the neuroprotective effects of Nigella sativa (NSt) ethanolic extract (200 mg/kg) and/or Telmisartan(Tel) (10 mg/kg) against fipronil (Fip) (9.7 mg/kg)-induced neurobehavioral toxicity in rats, besides exploring the underlying mechanistic signaling pathways. Our results showed …

Égypte, us (code pays fourni par la source)

Protective Effects of Niacin (Vitamin B3) on Pancreatic Functions, Hyperglycemia, Inflammatory Markers and Oxidative Stress in Alloxan-Induced Diabetic Rats

Mona Hafez, Neveen R. Ashoura, Asmaa A. Aboushouk, Aya H. Rohiem

bg, Égypte (code pays fourni par la source)

New Insights on the potential therapeutic effects of glibenclamide and Obeticholic acid against Alloxan-Induced diabetes mellitus in rat model

Asmaa A. Aboushouk, ‏Hebatallah M. Saad, Aya H. Rohiem, Dina R. S. Gad El-Karim

Égypte (code pays fourni par la source)