Zechen Zhang

Late follicular phase progesterone levels and in vitro fertilization and intracytoplasmic sperm injection outcomes

Hongfa Peng, Jingjing Jiang, Kaixuan Guo, Lei Jiang et autres

Objective: fertilization (IVF) and intracytoplasmic sperm injection (ICSI) cycles. Methods: This single-center, retrospective cohort study was conducted from January 2014 to December 2024 and included 24,868 women undergoing their first fresh embryo transfer following an IVF or ICSI cycle at a university-affiliated …

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Multifunctional 3D-printed Mg-doped bioactive glass/PLLA scaffolds with quercetin delivery for remodeling the osteoporotic microenvironment via osteogenic–angiogenic coupling and osteoclast inhibition

Wei Xiong, Zhenyu Wu, Yifeng Yuan, Yuyi Li et autres

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A commentary on “Stemness-associated WNT3A and EDN3 as key regulators of tumor progression and immunotherapy efficacy in LUAD”

Jinkun Li, Zechen Zhang, Xiaolin Shi

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Engineering a therapeutic deferoxamine-mesoporous silica-naringin/poly(L-lactic acid) scaffold to reverse ferroptosis-mediated imbalance and promote osteogenic differentiation in osteoporotic microenvironment

Wei Xiong, Yuyi Li, Yi‐Lin Yan, Tianci Wen et autres

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The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis

Zechen Zhang, Ying Li, Jinkun Li, Yifeng Yuan et autres

Background: Osteoporosis is a metabolic bone disease characterized by decreased bone mass and increased fracture risk. Bone turnover markers, such as osteocalcin (OC), undercarboxylated osteocalcin (ucOC), and other biochemical indicators, are important for assessing bone metabolism. Vitamin K2 influences bone metabolism by …

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VTA1 and breast cancer: a potential indicator for diagnostic and prognostic evaluation

Yongfeng Wang, Xinyue Yang, Xianglai Jiang, Hao Yang et autres

Abstract Objectives Vacuolar protein sorting-associated protein VTA1 homolog (VTA1) encodes a factor involved in multivesicular body trafficking. This investigation sought to determine if VTA1 might function as a diagnostic indicator, a standalone prognostic element, and a potential therapeutic target in breast cancer. …

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In vitro assessment of the osteogenic and antibacterial capabilities of Mg-MOF particles with encapsulated Levofloxacin within polydopamine

Wei Xiong, Yuxiang Zhou, Yuyi Li, Yifeng Yuan et autres

Infectious bone defect is a condition where infection and bone defect occur simultaneously. The simultaneous achievement of effective antimicrobial management and enhanced bone regeneration continues to present a major hurdle in musculoskeletal therapeutics. To address these limitations, we have developed a novel …

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In vitro assessment of the osteogenic and antibacterial capabilities of Mg-MOF particles with encapsulated levofloxacin within polydopamine

Wei Xiong, Yuxiang Zhou, Yuyi Li, Yifeng Yuan et autres

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Efficacy and safety of Epimedium total flavonoids for primary osteoporosis: a systematic review and meta-analysis

Jinkun Li, Xudong Huang, Yifeng Yuan, Haixin Zhang et autres

Background Epimedium total flavonoids (EF) have been recommended to be one of the effective components in Traditional Chinese Medicine (TCM) for the treatment of primary osteoporosis (POP) in China. Due to the lack of evidence-based medical evidence on the efficacy and safety …

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Effects of total flavonoids of Rhizoma Drynariae on biochemical indicators of bone metabolism: a systematic review and meta-analysis

Wei Li, Zechen Zhang, Yuyi Li, Zhenyu Wu et autres

Background Evidence shows that the total flavonoids of Rhizoma Drynariae (TFRD) can improve bone mineral density (BMD). However, there is no evidence to summarize the improvement of biochemical indicators of bone metabolism (BIBM). Methods The PubMed, Web of Science, Cochrane Library, Embase, …

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