Accès ouvert
2026
article
OpenAlex
A. Noll, Ali Javinani, Femke Slaghekke, Monique C. Haak et autres
INTRODUCTION: Selective fetal growth restriction (sFGR) is a major cause of perinatal morbidity and mortality in monochorionic diamniotic (MCDA) twin pregnancies. Current management relies on umbilical artery Doppler patterns in the smaller twin. These patterns are, however, inconsistent and do not represent …
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Accès ouvert
2025
article
OpenAlex
Jip A. Spekman, Eva Ros, Liesbeth Lewi, Femke Slaghekke et autres
BACKGROUND: Monochorionic (MC) twins share a single placenta which can be unequally shared, leading to selective fetal growth restriction (sFGR). Limited data is available on the prevalence and clinical consequences of proximate cord insertion (PCI) in sFGR pregnancies. OBJECTIVE: We aimed to …
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Accès ouvert
2024
article
OpenAlex
Yosuke Komatsu, E.J.T. Joanne Verweij, Eleonor Tiblad, Enrico Lopriore et autres
Abstract Nipocalimab is a neonatal fragment crystallizable (Fc) receptor (FcRn)—blocking monoclonal antibody that inhibits placental immunoglobulin G (IgG) transfer and lowers circulating maternal IgG levels. In an open-label, single-arm, phase 2 study, nipocalimab demonstrated evidence of safety and efficacy that support further …
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