Accès ouvert
2026
article
OpenAlex
Ibrahim Khalil, M Rafiqul Islam, Manisha Das, Sunjida Amin Promi et autres
Background: Heart failure (HF) remains a global health challenge, with distinct phenotypes – heart failure with reduced ejection fraction (HFrEF ≤40%) and heart failure with preserved ejection fraction (HFpEF ≥50%) – requiring tailored therapies. Vericiguat, a soluble guanylate cyclase stimulator, targets the …
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Accès ouvert
2026
article
OpenAlex
Ibrahim Khalil, M Rafiqul Islam, Sunjida Amin Promi, Arindam Das Joy et autres
BACKGROUND: Cardiovascular disease remains the leading cause of mortality worldwide, with residual cardiovascular (CVS) risk remaining high despite pharmacological interventions. Cholesteryl ester transfer protein (CETP) inhibitors have shown promise in improving lipid profiles, but their comparative effectiveness in reducing CVS outcomes remains …
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Accès ouvert
2026
article
OpenAlex
Sakib Abrar, Fabiha Rahman Spriha, Sajjad Ghanim Al‐Badri, Md. Imran Hossain et autres
ABSTRACT Parry‐Romberg Syndrome (PRS) is a rare disorder characterized by progressive unilateral facial atrophy, traditionally viewed as a localized scleroderma variant. Its rare coexistence with systemic lupus erythematosus (SLE) and autoimmune thyroiditis (AIT) suggests a broader inflammatory etiology, challenging the notion of …
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Accès ouvert
2026
article
OpenAlex
Ibrahim Khalil, Sakib Abrar, Shah Tanvir Ahmed, Md. Imran Hossain
ABSTRACT Kartagener's Syndrome (KS), a rare autosomal recessive disorder and a subset of Primary Ciliary Dyskinesia (PCD), is characterized by chronic sinusitis, bronchiectasis, and, in approximately 50% of cases, situs inversus. This condition arises from genetic mutations that impair motile cilia function, …
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Accès ouvert
2026
article
OpenAlex
Ibrahim Khalil, Sakib Abrar, I.M. Khalid Reza, Md. Imran Hossain et autres
Background: Multidrug-resistant tuberculosis (MDR-TB) remains a major public health challenge in South Asia, which bears a disproportionate global burden. Comprehensive, longitudinal analyses of MDR-TB mortality trends, stratified by country and sex, with forward-looking projections are limited. Methods: We conducted a retrospective analysis …
bd
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Accès ouvert
2026
article
OpenAlex
Sakib Abrar, Ibrahim Khalil, Md. Imran Hossain, Sunjida Amin Promi
Solid organ transplant recipients are at increased risk of acquiring serious infections. We present a case of a 48-year-old male with a history of renal transplantation in 2012, chronic kidney disease (CKD) Stage 4, hypertension, uncontrolled diabetes mellitus, and prior tuberculous pleural …
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Accès ouvert
2025
article
OpenAlex
Sakib Abrar, Ibrahim Khalil, Shah Tanvir Ahmed, Fabiha Rahman Spriha et autres
ABSTRACT Takayasu arteritis, a rare chronic large‐vessel vasculitis primarily affecting the aorta and its major branches, poses significant diagnostic and therapeutic challenges due to its heterogeneous manifestations and potential for severe vascular complications. This case report details a 40‐year‐old female presenting with …
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Accès ouvert
2025
article
OpenAlex
Sakib Abrar, Aiman Talukder, Md Mushfiqur Rahman Fahim, Fabiha Rahman Spriha et autres
Kallmann syndrome (KS) is a rare genetic disorder (1:4,000–10,000, predominantly in males) marked by hypogonadotropic hypogonadism and anosmia due to defective GnRH neuron migration. Mutations in KAL1, FGFR1, and other genes are implicated. A 20-year-old male presented with absent puberty and lifelong …
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Accès ouvert
2025
article
OpenAlex
Ibrahim Khalil, Md. Imran Hossain, Sakib Abrar, M. M. Akter et autres
Background: The HIV/AIDS epidemic remains a critical public health challenge in Bangladesh, with complex epidemiological trends and sex-specific disparities requiring detailed investigation to guide effective interventions. This study comprehensively analyzes the temporal dynamics of HIV/AIDS burden from 1990 to 2021 and employs …
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Accès ouvert
2025
article
OpenAlex
Sakib Abrar, Shah Tanvir Ahmed, Ibrahim Khalil, Md. Imran Hossain
Myasthenia gravis (MG) is a chronic autoimmune neuromuscular disorder that leads to muscle weakness and rapid fatigue, often exacerbated by thymoma, a tumor of the thymus gland. This case report presents the clinical management of a 40-year-old female with MG complicated by …
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Accès ouvert
2025
article
OpenAlex
Zahin Shahriar, Sakib Abrar, Soumik Roy, Tushar Kanti Bhadra
Adult-onset Henoch-Schönlein Purpura (HSP), although much less common than in children, tends to display a much more sinister clinical course. This case is about a 35-year-old female who presented with polyarthritis, abdominal pain, and purpuric rash- symptoms aligning with those of IgA …
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Accès ouvert
2025
review
OpenAlex
Ibrahim Khalil, M. Rafiqul Islam, Sunjida Amin Promi, Md Abu Sayed et autres
BACKGROUND: Hyperlipidemia, a key risk factor for cardiovascular disease, is characterized by elevated low-density lipoprotein cholesterol (LDL-C), triglycerides, and reduced high-density lipoprotein cholesterol (HDL-C). Cholesteryl ester transfer protein (CETP) inhibitors, such as anacetrapib, obicetrapib, evacetrapib, dalcetrapib, and torcetrapib, aim to improve lipid …
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