Zi-Qian Wang

[Determination of physical properties and calibration of discrete element simulation parameters for Jianwei Xiaoshi Granules].

Zi-Qian Wang, Fan Wu, Zhijian Zhong, Xiaorong Luo et autres

The construction method and simulation parameter settings for the discrete element model of Jianwei Xiaoshi Granules, as the primary material of Jianwei Xiaoshi Tablets, are not yet clear. The accuracy of the simulation model significantly influences the dynamic response characteristics between granules. …

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[Selection and reflection on ecological fine manufacturing model of traditional Chinese medicine under "dual carbon" goals].

Dong-Yin Yang, Zi-Qian Wang, Xin-Hao Wan, Ying Liu et autres

At present, China's traditional Chinese medicine(TCM) industry is developing rapidly with the support of modern science and technology. While promoting economic development and improving national health, it has brought multiple environmental problems. Under the "dual carbon" goals, the ecological fine manufacturing of …

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[Identification of CMAs of Jianwei Xiaoshi Tablet granules based on QbD concept and construction of their predictive model].

Xin-Hao Wan, Zhijian Zhong, Qing Tao, Zi-Qian Wang et autres

Identification of critical material attributes(CMAs) is a key issue in the quality control of large-scale TCM products like Jianwei Xiaoshi Tablets. This study focuses on the granules of Jianwei Xiaoshi Tablets, using tablet tensile strength as the primary quality attribute. A method …

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[Rapid non-destructive detection technology for traditional Chinese medicine preparations based on machine learning: a review].

Xin-Hao Wan, Qing Tao, Zi-Qian Wang, Dong-Yin Yang et autres

In recent years, with the increasing societal focus on drug quality and safety, quality issues have become a major challenge faced by the pharmaceutical industry, directly impacting consumer health and market trust. By combining multispectral imaging technology with machine learning, it is …

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[Current status, challenges, and development trends in intelligent manufacturing of traditional Chinese medicine solid preparations].

Zi-Qian Wang, Yuanhui Li, Xuecheng Wang, Xiaorong Luo et autres

The intelligent manufacturing of traditional Chinese medicine(TCM) solid preparations is an important direction in the current development of the TCM industry. TCM enterprises are fervently pursuing intelligent manufacturing and digital transformation, and new equipment and technologies are empowering the development of this …

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[Application of discrete element method (DEM) in pharmaceutical process of solid traditional Chinese medicine preparations].

Yi-Feng Wu, Zi-Qian Wang, Xin-Hao Wan, Hui-Quan Hu et autres

In recent years, the application of numerical simulation in the research and development(R&D) as well as the pharmaceutical processes of new drugs has expanded considerably. The discrete element method(DEM), an important approach among numerical simulation methods, offers an effective tool for the …

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[Critical influencing factors on quality of traditional Chinese medicine preparations from perspective of process and equipment].

Xin-Hao Wan, Zi-Qian Wang, Dong-Yin Yang, Ming Yang et autres

The quality of traditional Chinese medicine preparations is directly related to the safety of patients. Among the various factors, the process and corresponding critical equipment are critical factors influencing the quality of the preparations. To improve the quality of traditional Chinese medicine …

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[Scientific connotation of temperature control in processing of Chinese medicinal materials based on theory of quality evaluation through morphological identification].

Xuan Cao, Yutian Zhang, Zhenfeng Wu, Liu-Feng Xu et autres

Processing of Chinese medicinal materials is an important part in the Chinese medicine heritage, and the temperature control in the processing has a direct impact on the quality and efficacy of traditional Chinese medicines. However, the processing of Chinese medicinal materials has …

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[Current situation and development trend of digital traditional Chinese medicine pharmacy].

Zhenfeng Wu, Shu-Jie Yang, Yiqin Yang, Zi-Qian Wang et autres

The 21st century is a highly information-driven era, and traditional Chinese medicine(TCM) pharmacy is also moving towards digitization and informatization. New technologies such as artificial intelligence and big data with information technology as the core are being integrated into various aspects of …

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[Current status, trends, and challenges of continuous manufacturing technology for oral traditional Chinese medicine solid preparations].

Zi-Qian Wang, Xuecheng Wang, Zhijian Zhong, Zhenfeng Liu et autres

In recent years, continuous manufacturing technology has attracted considerable attention in the pharmaceutical industry. This technology is highly sought after for its significant advantages in cost reduction, increased efficiency, and improved productivity, making it a growing trend in the future of the …

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CCDC 1842251: Experimental Crystal Structure Determination

Cui‐Bing Bai, Fan, Hai-Yun, Rui Qiao, Shengnan Wang et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …