Accès ouvert
2026
article
OpenAlex
Xiangyun Dang, Zhongxin Jin, Yafeng Zhao, Yu Wang et autres
BACKGROUND: Chronic kidney disease (CKD) is associated with a substantially elevated risk of mortality. Although GrimAge acceleration (GAA) and metabolic syndrome (MetS) are both implicated in this risk, their combined impact and the underlying biological mechanisms remain poorly understood. METHODS: This study …
cn
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Accès ouvert
2025
article
OpenAlex
Xiangyun Dang, Guiqing Xu, Huixian Li, Yiqun Hao et autres
Background Chronic kidney disease (CKD) is closely linked to systemic inflammation and accelerated cellular aging. However, the role of the systemic inflammation response index (SIRI) and leukocyte telomere length (LTL), a biomarker of cellular aging, in the development and progression of CKD …
cn, us
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Accès ouvert
2025
preprint
OpenAlex
Xiangyun Dang, Danfeng Ren, Guiqing Xu, Yafeng Zhao et autres
Abstract Background Cardiovascular-kidney-metabolic (CKM) syndrome is characterized by complex pathophysiological interactions among cardiovascular diseases, and chronic kidney disease. Although there is evidence linking dietary antioxidants to the reduction of oxidative stress, comprehensive studies investigating relationships between CKM syndrome and antioxidants remain limited. …
cn
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Accès ouvert
2025
article
OpenAlex
Danfeng Ren, Xiangyun Dang, Tianzhi Ni, Jingwen Zhou et autres
Background As the most abundant protein in plasma, albumin (ALB) presents close association with prognosis of septic patients. Whereas, the benefit and the target level of ALB infusion remain controversial. Methods We conducted a retrospective investigation to assess whether on-treatment ALB levels …
cn
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2024
article
OpenAlex
Jin Li, Wanhong Lu, Xiangyun Dang
Background: Malignant hypertension (MHT) is a group of syndromes characterized by severe hypertension and acute microvascular injury, often accompanied by thrombotic microangiopathy (TMA). This study aimed to establish a high-quality and standardized historical prospective study cohort to preliminarily investigate the possible mechanism …
cn
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Accès ouvert
2024
article
OpenAlex
Li Jin, Xueying Liu, Huixian Li, Xiangyun Dang et autres
Li Jin, Xueying Liu, Huixian Li, Xiangyun Dang, Zhigang Wang, Dan Niu, Xiaotian Zhang, Jiping Sun, Dapeng Hao, Wanhong Lu; Obinutuzumab is Effective for th
cn
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Accès ouvert
2023
article
OpenAlex
Huixian Li, Wanhong Lu, Xinfang Xie, Ying Wang et autres
INTRODUCTION: High serum phosphorus level has been reported to be a risk factor for disease progression in patients with chronic kidney disease, whereas, its role in IgA nephropathy (IgAN) still remains uncertain. This study aimed to investigate the association between serum phosphorus …
cn
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2023
article
OpenAlex
Wanhong Lu, Xiangyun Dang, Chao Liu, Zhigang Wang et autres
INTRODUCTION: A large proportion of patients initiated hemodialysis with a central vein catheter rather than a permanent vascular access which was recommended by guidelines. One major barrier was the paucity of evidence regarding the optimal timing of vascular access creation in predialysis …
cn
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