Bernardino Bottalico

Effect of centre volume on pathological outcomes and postoperative complications after surgery for colorectal cancer: results of a multicentre national study

Matteo Rottoli, Antonino Spinelli, Gianluca Pellino, Giacomo Calini et autres

BACKGROUND: The association between volume, complications and pathological outcomes is still under debate regarding colorectal cancer surgery. The aim of the study was to assess the association between centre volume and severe complications, mortality, less-than-radical oncologic surgery, and indications for neoadjuvant therapy. …

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Colorectal Cancer Stage at Diagnosis Before vs During the COVID-19 Pandemic in Italy

Matteo Rottoli, Gianluca Pellino, Maria Elena Flacco, Cecilia Acuti Martellucci et autres

Importance: Delays in screening programs and the reluctance of patients to seek medical attention because of the outbreak of SARS-CoV-2 could be associated with the risk of more advanced colorectal cancers at diagnosis. Objective: To evaluate whether the SARS-CoV-2 pandemic was associated …

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Increased fetal blood pressure response to maternal norepinephrine after pharmacological inhibition f norepinephrine uptake in pregnant sheep

S. R. Hansson, Bernardino Bottalico, Isis Amer‐Wåhlin, Karel Maršál et autres

OBJECTIVE: Norepinephrine (NE) is elevated in pregnancies complicated by preeclampsia (PE). Specific uptake of NE by the NE transporter (NET) plays a central role as regulator of NE levels. Expression of NET is reduced in placentas from PE pregnancies. To study adverse …

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Norepinephrine Transporter (NET), Serotonin Transporter (SERT), Vesicular Monoamine Transporter (VMAT2) and Organic Cation Transporters (OCT1, 2 and EMT) in Human Placenta from Pre-eclamptic and Normotensive Pregnancies

Bernardino Bottalico, I. Larsson, Jana Brodszki, Edgar Hernández‐Andrade et autres

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