Linya Huang

Clonorchis sinensis-derived extracellular vesicle (CsEV) miRNA Csi-miR-190-3p exerts dual roles in cholangiocarcinoma progression via cell cycle modulation and CXCL5 signaling suppression

Anyuan Xu, Aoxun Wu, Xiaowen Pan, Linya Huang et autres

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Dual Oncogenic Mechanisms of Clonorchis sinensis-Derived Csi-miR-125a in Promoting Cholangiocarcinoma Progression via BAK1 Targeting and ERK Activation

Aoxun Wu, Anyuan Xu, Linya Huang, Shu Fang et autres

Cholangiocarcinoma (CCA) is an aggressive malignancy with a poor prognosis that is strongly associated with chronic Clonorchis sinensis (C. sinensis, Cs) infection; however, its underlying molecular mechanisms remain elusive. Recent studies suggest that C. sinensis-derived extracellular vesicles (CsEVs) play a crucial role …

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Piezoelectric stepped-plate resonators vibrating at lateral modes for direct viscosity determination in liquids

Linya Huang, Dejiang Lu, X. L. Han, HePing Wu et autres

Precise viscosity measurement in liquid media remains a critical challenge for micromachined resonant sensors. This primarily results from the inherent coupling between viscosity and density in hydrodynamic interactions, which limits independent quantification of viscosity. This work presents an aluminum nitride (AlN) piezoelectric …

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and cholangiocarcinoma: molecular mechanisms and biomarker advances

Chenlin Huang, Yinjuan Wu, Aoxun Wu, Linya Huang et autres

Clonorchis sinensis, a common food-borne liver fluke in East Asia, is a Group 1 carcinogen strongly linked to cholangiocarcinoma. In recent years, molecular biology and multi-omics studies have revealed that this parasite drives chronic inflammation of the bile duct epithelium, epigenetic abnormalities, …

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Clonorchis sinensis and cholangiocarcinoma: molecular mechanisms and biomarker advances

Chenlin Huang, Yue Wu, Aiming Wu, Linya Huang et autres

Clonorchis sinensis, a common food-borne liver fluke in East Asia, is a Group 1 carcinogen strongly linked to cholangiocarcinoma. In recent years, molecular biology and multi-omics studies have revealed that this parasite drives chronic inflammation of the bile duct epithelium, epigenetic abnormalities, …

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Exploring the cost implications of different treatment modalities for uterine fibroids under the DRG system

Linya Huang, Yuxian Nie, Qiuling Shi, Su Yan et autres

This paper, based on data from inpatient medical records with uterine fibroids (ICD-10: D25) from the medical record homepages of secondary and higher-level hospitals in Sichuan Province between 2016 and 2024, investigated differences in medical resource consumption and costs between high-intensity focused …

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Highly uniform and ultra-sensitive graphene hybrid SERS substrates fabricated by colloidal lithography

He‐Ping Wu, Linya Huang, Luyue Jiang, Zixuan Li et autres

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Social isolation in relation to the incidence and dynamic progression of frailty in the oldest old: a trajectory analysis of a nationwide cohort

Junyi Wang, Ya‐Fu Yu, Lang Xu, Xinyan Xie et autres

BACKGROUND: There is still a lack of evidence examining the association of behavioral and social factors with frailty transitions and mortality. We investigated whether social isolation is associated with different progressions and outcomes of frailty among community-dwelling older adults. METHODS: This community-based …

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Modeling the distribution of the invasive snail Physella acuta in China: implications for ecological and economic impact

Yingxuan Yin, Ao Xu, Xiaowen Pan, Qing He et autres

The invasive freshwater snail Physella acuta poses significant threats to the ecological environment, public health safety, and the agricultural and forestry economy. Gaining insight into their geographical spread in China under current and future climate scenarios is crucial for effective monitoring and …

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Crude Oil Futures Price Forecasting Based on Variational and Empirical Mode Decompositions and Transformer Model

Linya Huang, Xite Yang, Yongzeng Lai, Ankang Zou et autres

Crude oil is a raw and natural, but nonrenewable, resource. It is one of the world’s most important commodities, and its price can have ripple effects throughout the broader economy. Accurately predicting crude oil prices is vital for investment decisions but it …

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Exploring the psychological impact of the 2022 SARS‐CoV‐2 Omicron variant outbreak in China

Gangbin Han, Guirong Cheng, Feifei Hu, Chun-Li Li et autres

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Economic policy uncertainty, macroeconomic shocks, and systemic risk: Evidence from China

Xite Yang, Qin Zhang, Haiyue Liu, Zihan Liu et autres

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