O J.M.

Effects of Targeting the Cullin RING E3 Ubiquitin Ligase Using MLN4924 on the Alloimmune Response

Bayan Alsairafi, C.L. Miller, O J.M., G. Benichou et autres

Purpose: We previously reported that DEPTOR is expressed in murine CD4+ T cells and that it is functional in Treg stability via its effects to augment Foxp3 expression and regulate cellular metabolism. MLN4924 (MLN) is a Cullin Ring E3 ligase inhibitor that …

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Successful Use of Anti-IL-6R Therapy to Achieve Cardiac Allograft Tolerance in Non-Human Primates

Cynthia L. Miller, K.J. Ahrens, O J.M., P.M. Patel et autres

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Inducing Donor MHC Chimerism with Bone Marrow Derived Exosomes in Non-Human Primates

P.M. Patel, B.A. Gonzalez-Nolasco, Jeremy Morrissette, A. Prunevieille et autres

Detrimental Effects of Donor Brain Death on Tolerance Induction May Be Eliminated by Delaying Mixed Chimerism in Non-Human Primates

O J.M., W. Sommer, P. Kurt, J.T. Paster et autres

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Inducing Donor MHC Chimerism with Bone Marrow Derived Exosomes in Non-Human Primates

Parth Patel, B.A. Gonzalez-Nolasco, J.A. Morrissette, Aurore Prunevieille et autres

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The effect of concanavalin A on the replication of rotavirus (SA-11) in cell culture

Hasenack Beatriz S., Bauer John J., Lauretti Flávio, Melo Fernando L. de et autres

Rotavirus (RV) strain SA-11 was studied with respect to its infectivity in MA-104 cell cultures and the effect of concanavalin A (ConA). Receptors for ConA at the surface of MA-104 cell were determined by fluorescence assay and specifically inhibited by D-mannose. The …