Li Sun

Efficacy and safety of tocilizumab in Chinese patients with systemic juvenile idiopathic arthritis: a multicentre phase IV trial

Caifeng Li, Xuemei Tang, Zhixuan Zhou, Li Sun et autres

Abstract Objectives Given the limited tocilizumab (TCZ) treatment data for systemic juvenile idiopathic arthritis (sJIA) in China, we evaluated the long-term efficacy and safety of TCZ in Chinese patients with sJIA. Method In this multicentre, interventional Phase IV study, patients with sJIA …

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Network meta-analysis of first-line therapy for NSCLC patients with liver metastases: Implications for improving prognosis

Li Sun, Shuling Zhang, Le‐Tian Huang, Jietao Ma et autres

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Monogenic autoinflammatory disease-associated cardiac damage

Qijiao Wei, Li Sun

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Novel loss-of-function mutations in TNFAIP3 gene in patients with lupus nephritis

Changming Zhang, Xu Han, Li Sun, Sirui Yang et autres

ABSTRACT Background Heterozygous loss-of-function mutations in the tumour necrosis factor alpha induced protein 3 (TNFAIP3) gene cause an early-onset auto-inflammatory disease named haploinsufficiency of A20 (HA20). Here we describe three unrelated patients with autoimmune lupus nephritis (LN) phenotypes carrying three novel mutations …

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Expanding the spectrum of A20 haploinsufficiency in two Chinese families: cases report

Guomin Li, Haimei Liu, Wanzhen Guan, Hong Ming Xu et autres

BACKGROUND: The association between mutations in the TNFAIP3 gene and a new autoinflammatory disease (called A20 haploinsufficiency, HA20) has recently been recognized. Here, we describe four patients with HA20 from two unrelated Chinese families. CASE PRESENTATION: A total of four patients from …

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