Naomi Uchiyama

Elevated Plasma Adrenomedullin Levels in Patients with Unresectable Advanced Gastrointestinal Cancers

Yoshinori Ozono, Hotaka Tamura, Kazuo Kitamura, Ayumu Hosokawa et autres

Background/Objectives: Adrenomedullin (AM) is a circulating peptide involved in tumor progression, angiogenesis, and fibrosis. However, its clinical utility as a biomarker in gastrointestinal cancers remains unclear. Methods: This single-center prospective observational study included patients with unresectable advanced gastrointestinal cancers (esophageal, gastric, colorectal, …

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A novel 6 Fr inside biliary stent system for perihilar biliary drainage

Hiroshi Kawakami, Naomi Uchiyama, Hiroshi Hatada

Endoscopic biliary drainage (BD) is commonly performed in patients with perihilar biliary obstruction; however, the most appropriate method remains controversial. The plastic stent technique involves placing the tip of inside stent within the bile duct. Recently, the clinical outcomes of the inside …

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Tofogliflozin attenuates liver steatosis and fibrosis in non-diabetic non-alcoholic steatohepatitis mice

Yoshinori Ozono, Hiroshi Kawakami, Hiroshi Hatada, Naomi Uchiyama et autres

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease with increasing global prevalence. Although diabetes is a major factor in NAFLD progression, up to 75% of the patients with NAFLD do not have diabetes. Tofogliflozin (Tofo), a …

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【胆膵内視鏡処置具ガイド2025】私のミニマルセットはこれ! 結石除去(2)

Hiroshi Kawakami, Naomi Uchiyama, Hiroshi Hatada

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Hepatic focal nodular hyperplasia after liver transplantation: case report and review of literature

Kenichi Nakamura, Yoshinori Ozono, Satoru Hasuike, Hiroshi Hatada et autres

Patients with decompensated cirrhosis complicated by hepatocellular carcinoma (HCC) or those who have undergone liver transplantation following liver failure after HCC treatment should continue to receive post-transplant surveillance. Any new liver tumor must be carefully evaluated to determine whether it is a …

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Optimal Number of Needle Punctures in EUS-FNA/B with ROSE for Solid Pancreatic Lesions

Naomi Uchiyama, Hiroshi Kawakami, Yoshinori Ozono, Hiroshi Hatada et autres

Background and Objectives: Endoscopic ultrasonography (EUS)-guided fine-needle aspiration/biopsy (FNA/B) is widely used for solid pancreatic lesions; however, the optimal number of needle punctures required to achieve high diagnostic accuracy remains unclear. This study aimed to identify the ideal number of punctures required …

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胃gastrointestinal stromal tumorに対するEUS-FNA後出血に対するAPC止血により門脈ガス血症を呈した1例

Hiroshi Hatada, Hiroshi Kawakami, Naomi Uchiyama, 宗一郎 小川 et autres

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胆道専門医講座 膵・胆管合流異常(第2回) 膵・胆管合流異常の診断

Hiroshi Kawakami, Hiroshi Hatada, Naomi Uchiyama, Soichiro Ogawa

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Multiple intrahepatic artery aneurysms during the treatment for IgG4-related sclerosing cholangitis: A case report

Hotaka Tamura, Yoshinori Ozono, Keisuke Uchida, Naomi Uchiyama et autres

BACKGROUND: The purpose of this case report is to describe a case of multiple intrahepatic artery aneurysms during treatment for IgG4-related sclerosing cholangitis (IgG4-SC) and to provide information for daily practice. CASE SUMMARY: A 64-year-old Japanese woman was diagnosed with IgG4-SC five …

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Evaluation of the optical and electrical properties of (C8BTBT)(F4TCNQ) charge-transfer complexes according to film formation temperatures during solution coating

Naomi Uchiyama, Yuji Matsuura

Abstract This study focused on (C8BTBT)(F4TCNQ) charge-transfer complexes, where C8BTBT is 2,7-dioctyl[1]benzothieno[3,2-b][1]benzothiophene and F4TCNQ represents fluorinated derivatives of 7,7,8,8,-tetracyanoquinodimethane. These complexes exhibit excellent thermal and atmospheric stability and near-infrared absorption, serving as transparent thin films for photoelectric conversion. Here, we sought to …

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An autopsy case of an adult woman with Rapid-Onset Obesity with Hypoventilation, Hypothalamic, Autonomic Dysregulation, and Neuroendocrine Tumors (ROHHAD(NET)) syndrome developing nonalcoholic steatohepatitis and hepatocellular carcinoma: A case report

Satoru Hasuike, Yoshinori Ozono, Keisuke Uchida, Souichiro Ogawa et autres

BACKGROUND: Nonalcoholic steatohepatitis (NASH) is an important etiology of hepatocellular carcinoma (HCC), and there is no established therapy for this syndrome. Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, autonomic dysregulation, and neural crest tumor (ROHHAD(NET)) is an extremely rare syndrome considered to be …

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Reactivation of hepatitis C virus caused by steroid monotherapy for sudden deafness

Hiroki Kaneko, Yoshinori Ozono, Hisayoshi Iwakiri, Hiroshi Hatada et autres

Hepatitis C virus (HCV) reactivation has been reported to be caused due to several anticancer drugs and immunosuppressive agents; however, HCV reactivation after steroid monotherapy has rarely been reported. Here, we report the case of a 65-year-old Japanese man with HCV infection …

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