Chao-Wen Lin

Optical coherence tomography angiography characteristics of microvascular retinal alterations and the relationship with visual impairment in different patterns of retinitis pigmentosa

Hsu-Hang Yeh, Chia-Yi Cheng, Ting-Chieh Ko, Chang‐Hao Yang et autres

Abstract: PURPOSE: The purpose of the study was to evaluate macular microvascular alterations using optical coherence tomography angiography (OCTA) in typical retinitis pigmentosa (RP) patients with and without isolated macular lesions, and to assess their relationship with best-corrected visual acuity (BCVA). MATERIALS …

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Five-Year Results With Patisiran for Hereditary Transthyretin Amyloidosis With Polyneuropathy

David H Adams, Jonas Wixner, Michael J. Polydefkis, John L. Berk et autres

Importance: There is a lack of long-term efficacy and safety data on hereditary transthyretin amyloidosis with polyneuropathy (hATTR-PN) and on RNA interference (RNAi) therapeutics in general. This study presents the longest-term data to date on patisiran for hATTR-PN. Objective: To present the …

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Elevated α-synuclein and NfL levels in tear fluids and decreased retinal microvascular densities in patients with Parkinson’s disease

Chao-Wen Lin, Tzu-Ting Lai, Szu‐Ju Chen, Chin‐Hsien Lin

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Vitreous cytology as the only diagnostic evidence of central nervous system involvement in a patient with isolated leukemic infiltrative optic neuropathy

Wenyi Wang, Chao-Wen Lin

A 29-year-old female with treated acute lymphoblastic leukemia in remission presented with blurred vision and pain on movement of the right eye. On examination, visual acuity was 20/25 in the right eye and 20/20 in the left eye. Direct ophthalmoscopy revealed that …

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Clinical Course and Treatment Response of Neuromyelitis Optica Spectrum Disease: An 8-Year Experience

Chao-Wen Lin, I-Hung Lin, Ta‐Ching Chen, Jieh‐Ren Jou et autres

Purpose: To report the clinical course and treatment response in a cohort of patients with neuromyelitis optica spectrum disorder (NMOSD) from a single referral center in Taiwan. Design: Case series. Methods: All NMOSD patients who received treatment and follow-up checks at National …

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Update on ocular myasthenia gravis in Taiwan

Lin‐Chung Woung, Chao-Wen Lin, Ta‐Ching Chen, Jieh‐Ren Jou

Myasthenia gravis (MG) is an autoimmune disease involving the neuromuscular junction. Autoantibodies to the acetylcholine receptor or, less frequently, to muscle-specific kinase, attack against the postsynaptic junctional proteins, resulting in fluctuating and variable weakness of muscles. Extraocular, levator palpebrae superioris, and orbicularis …

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