Xuhui Cong

Development and validation of a risk prediction model for postoperative pneumonia in elderly non-cardiac surgery patients: a retrospective cohort study

Xuhui Cong, Xuli Zou, Lulu Jiang, Ruilou Zhu et autres

Abstract Postoperative pneumonia (POP) is a prevalent, severe complication in elderly noncardiac surgical patients, linked to extended hospital stays, increased healthcare costs, and higher mortality. Existing predictive models are often limited by single-center data, small cohorts, or restricted variables, highlighting the need …

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Neuroactive Steroids Hold Promise as Innovative Anesthetics

Tian Mao, Ting Li, Ruilou Zhu, Xuhui Cong et autres

ABSTRACT Previous studies have shown that general anesthetics have neurotoxic effects on developing brains. Reducing the toxicity of anesthetics or finding nonneurotoxic anesthetics is a major challenge in anesthetic research. Neuroactive steroids (NASs) are active steroids in nervous tissue that regulate the …

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Development and validation of an interpretable risk prediction model for perioperative ischemic stroke in noncardiac, nonvascular, and nonneurosurgical patients: a retrospective study

Xuhui Cong, Xuli Zou, Ruilou Zhu, Yubao Li et autres

Background: Perioperative stroke is a severe complication for patients undergoing non-cardiac, non-vascular, and non-neurosurgical surgeries, resulting in significant morbidity and mortality. Despite its clinical relevance, effective predictive models for stroke risk in this population are scarce. This study seeks to develop and …

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Development and validation of a risk prediction model for perioperative acute kidney injury in non-cardiac and non-urological surgery patients: a retrospective cohort study

Xuhui Cong, Xuli Zou, Ruilou Zhu, Yubao Li et autres

Background This study presents a predictive model designed to fill the gap in tools for predicting perioperative acute kidney injury (AKI) in patients undergoing non-cardiac, non-urological surgeries, with the goal of improving clinical decision-making and patient outcomes. Methods A retrospective cohort of …

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Development and validation of a machine learning-based model for perioperative stroke prediction in noncardiac, nonvascular, and nonneurosurgical patients

Xuhui Cong, Xuli Zou, Ruilou Zhu, Yubao Li et autres

Introduction: Perioperative stroke is a rare but severe complication that significantly impacts postoperative recovery and survival. This study aimed to develop a machine learning-based predictive model for perioperative stroke risk in patients undergoing noncardiac, nonvascular, and nonneurosurgical procedures. Methods: This retrospective cohort …

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From neurotoxicity to neuroprotection: Rethinking GABAAR-targeting anesthetics

Yubao Li, Hongliang Yang, Lu Liu, Lulu Jiang et autres

Abstract The brain growth spurt (BGS) represents a pivotal window in neurodevelopment, defined by rapid neurogenesis, heightened synaptogenesis, and the dynamic establishment of neural networks. During this phase, heightened brain plasticity significantly enhances learning and memory abilities, while also increasing the brain’s …

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Development with external validation of a prediction model for postoperative acute kidney injury following noncardiac surgery in elderly patients

Xiaoying Zhang, Xianghan Ruan, Yu Qi Yao, Tongyan Sun et autres

STUDY OBJECTIVE: To develop and externally validate a risk prediction model for postoperative acute kidney injury (PO-AKI) in elderly patients undergoing noncardiac surgery, addressing the current gap in predictive tools for this vulnerable population. DESIGN: A multicenter retrospective cohort study presented according …

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Risk factor analysis and creation of an externally-validated prediction model for perioperative stroke following non-cardiac surgery: A multi-center retrospective and modeling study

Yulong Ma, Siyuan Liu, Faqiang Zhang, Xuhui Cong et autres

BACKGROUND: Perioperative stroke is a serious and potentially fatal complication following non-cardiac surgery. Thus, it is important to identify the risk factors and develop an effective prognostic model to predict the incidence of perioperative stroke following non-cardiac surgery. METHODS AND FINDINGS: We …

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Development and Validation of an Interpretable Risk Prediction Model for Perioperative Ischemic Stroke in Noncardiac, Nonvascular, and Nonneurosurgical Patients: A Retrospective Study

Xuhui Cong, Xuli Zou, Ruilou Zhu, Yubao Li et autres

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The way to improve the quality of new smart city public service under the demand heterogeneity

Kaitao Cao, Jingru Yang, Xuhui Cong

Due to the diversity, difference and dynamics of residents' needs, the improvement of public service quality is faced with many challenges. Therefore, it is of great practical significance to improve the path of public service quality of new smart city under the …

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High flow nasal cannula for patients undergoing bronchoscopy and gastrointestinal endoscopy: A systematic review and meta-analysis

Mingyang Sun, Mengrong Miao, Yaqian Han, Yi Yang et autres

Background High flow nasal cannula is gaining increasingly used in patients undergoing endoscopic procedures. We undertook this systematic review and meta-analysis to determine whether high flow nasal cannula (HFNC) could effectively minimize the risk of hypoxemia as compared with conventional oxygen therapy …

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Inhaled nitric oxide and acute kidney injury risk: a meta-analysis of randomized controlled trials

Junqiu Wang, Xuhui Cong, Mengrong Miao, Yi Yang et autres

Purpose There are conflicting results as to the effect of inhaled nitric oxide (iNO) therapy on the risk of acute kidney injury (AKI). The aim of this study was to perform a meta-analysis to assess the updated data.Methods We systematically searched Web …

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