Ikuko Goto

Zymosan‐Treated SKG Mice: Assessing Effects of Systemic Inflammation on the Temporomandibular Joint

Kaito Uryu, Yasumasa Kakei, Sho Sendo, Ikuko Goto et autres

OBJECTIVES: The effects of systemic inflammation on the temporomandibular joint (TMJ) are poorly understood. This study aimed to establish a mouse model to study the effects of systemic inflammation on the TMJ. MATERIALS AND METHODS: SKG mice, a BALB/c strain with spontaneous …

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Author response for "Zymosan‐Treated SKG Mice: Assessing Effects of Systemic Inflammation on the Temporomandibular Joint"

Kaito Uryu, Yasumasa Kakei, Sho Sendo, Ikuko Goto et autres

Author response for "Zymosan‐Treated SKG Mice: Assessing Effects of Systemic Inflammation on the Temporomandibular Joint"

Kaito Uryu, Yasumasa Kakei, Sho Sendo, Ikuko Goto et autres

Can CT predict the development of oroantral fistula in patients undergoing maxillary third molar removal?

Eiji Iwata, Takumi Hasegawa, Masaki Kobayashi, Akira Tachibana et autres

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A Case of Medication-related Osteonecrosis of the Jaw

Eiji Iwata, Masaya Akashi, Ikuko Goto, Shungo Furudoi et autres

For patients undergoing treatment for bone metastases by the administration of drugs such as bisphosphonates (BP), osteonecrosis of the jaw is a serious side effect. In recent years, it has been reported that some drugs other than BP also cause osteonecrosis of …

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A case of methotrexate-associated lymphoproliferative disorder with osteonecrosis of the jaw

Ikuko Goto, Shungo Furudoi, Jyunichiro TAKEUCHI, Masaru Ishida et autres

We report a case of methotrexate-associated lymphoproliferative disorder （MTX-LPD） with osteonecrosis of the maxilla. A 74-year-old woman who had been treated for 10 years with methotrexate （MTX） and steroids for rheumatoid arthritis was found to have pain after tooth extraction of the …

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集団把握力を養成する課外型インターンシップカリキュラムの開発 : 教育実習・ボランティア体験の限界への挑戦

郁子 後藤, Ikuko Goto

Regarding the inability of beginning elementary school teachers to immediately become independent\nteachers at school, one survey shows that the current teacher training programs in the four-year training at\nuniversities fail to equip undergraduates who aspire to become teachers with the minimum qualifications and\nabilities, …

Degradation of p21 Cip1 through anaphase-promoting complex/cyclosome and its activator Cdc20 (APC/C Cdc20) ubiquitin ligase complex-mediated ubiquitylation is inhibited by cyclin-dependent kinase 2 in cardiomyocytes

Kazuhiko YAMADA, Mimi Adachi, Ikuko Goto, masayoshi Iizuka et autres

Cyclin-dependent kinase inhibitor p21 Cip1 plays a crucial role in regulating cell cycle arrest and differentiation. It is known that p21 Cip1 increases during terminal differentiation of cardiomyocytes, but its expression control and biological roles are not fully understood. Here, we show …

Degradation of p21Cip1 through Anaphase-promoting Complex/Cyclosome and Its Activator Cdc20 (APC/CCdc20) Ubiquitin Ligase Complex-mediated Ubiquitylation Is Inhibited by Cyclin-dependent Kinase 2 in Cardiomyocytes

Kazuhiko Yamada, Mimi Tamamori‐Adachi, Ikuko Goto, Masayoshi Iizuka et autres

Cyclin-dependent kinase inhibitor p21Cip1 plays a crucial role in regulating cell cycle arrest and differentiation. It is known that p21Cip1 increases during terminal differentiation of cardiomyocytes, but its expression control and biological roles are not fully understood. Here, we show that the …

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A case of IgG4-related chronic sclerosing sialadenitis of the submandibular gland suggesting a complication of autoimmune pancreatitis

Ikuko Goto, Noboru Akazawa, Sinsuke Tanaka

We report a case of IgG4-related chronic sclerosing sialadenitis （CSS） of the submandiblar gland. A 68-year-old man was found to have left submandibular swelling during postoperative follow-up for tongue cancer. We examined the fine needle aspiration （FNA）, MRI, CT and cervical ultrasonographic …

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Differential regulation of cyclin D1 and D2 in protecting against cardiomyocyte proliferation

Mimi Tamamori‐Adachi, Ikuko Goto, Kazuhiko Yamada, Shigetaka Kitajima

Cardiomyocytes withdraw from cell cycle after terminal differentiation due in part to impaired nuclear import of cyclin D1. Thus, we have previously shown that expression of nuclear localization signal-tagged cyclin D1 (D1NLS) and cyclin-dependent kinase 4 promotes cardiomyocyte proliferation both in vitro …

Differential regulation of cyclin D1 and D2 in protecting against cardiomyocyte proliferation

Mimi Adachi, Ikuko Goto, Kazuhiko YAMADA, Shigetaka Kitajima

Cardiomyocytes withdraw from cell cycle after terminal differentiation due in part to impaired nuclear import of cyclin D1. Thus, we have previously shown that expression of nuclear localization signal-tagged cyclin D1 (D1NLS) and cyclin-dependent kinase 4 promotes cardiomyocyte proliferation both in vitro …