Accès ouvert
2025
preprint
OpenAlex
Naoki Yamamoto, Toshio Nakamura, Ananda K. Maharjan, Hironori Sato
Horqin was a key region in eastern Mongolia that Genghis Khan bestowed upon his brothers, Khasar and others. Around 1935, when Japan ruled Manchukuo, a unique Mongolian helmet was discovered here by Dr. Noboru Yamamoto. Though bearing a Qing prince’s name in …
jp, np
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2025
article
OpenAlex
Nozomu Tsuchiya, Fumikazu Ikemori, Kazuo Kawasaki, Reina Yamada et autres
High Resolution Image Download MS PowerPoint Slide Combustion-derived magnetite has recently attracted attention for its health risks and potential impact on atmospheric heating/cooling. This study provides new observational insights into the relationship between black carbon (BC) and magnetite at a remote site …
jp
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Accès ouvert
2025
article
OpenAlex
Yuho Yamauchi, Mizuka Kobayashi, Tomoki Oguro, Narumi Takaichi et autres
米糠は玄米から白米を精米する際に得られる副産物であり,さまざまな機能性成分が含まれている。近年,米糠由来成分の美容分野における有効性に焦点を当てた研究が盛んに行われ,その皮膚における機能が明らかにされてきた。本研究では,代表的な米糠由来成分であるイノシトール,フェルラ酸,γ-オリザノールを対象とし,ヒト皮膚における透過性を明らかにすることを目的とした。イノシトール,フェルラ酸,γ-オリザノールを1%配合した化粧品製剤をそれぞれ別々の拡散セルに設置したヒト皮膚組織に適用し,適用後2,4,6時間時点の透過量を測定した。その結果,適用から6時間までの単位皮膚面積あたりの累積透過量はフェルラ酸が352.67±234.45 μg/cm2,イノシトールが162.15±66.89 μg/cm2,γ-オリザノールが46.10±12.60 μg/cm2となった。本試験の結果から,これらの米糠由来成分は皮膚の角層バリアを透過して皮膚内の標的作用部位へと到達し,美容効果を発揮することが期待された。
2024
article
OpenAlex
Genki Inoue Matsumoto, Eisuke Honda, Keisuke Ito, Ijin Kang et autres
jp
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Accès ouvert
2024
article
OpenAlex
Toshiaki Toshima, Ryo Inada, Shinya Sakamoto, Eri Takeda et autres
BACKGROUND: Goblet cell carcinoid (GCC) of the appendix is a rare tumor characterized by neuroendocrine and adenocarcinoma features. Accurate preoperative diagnosis is very difficult, with most patients complaining mainly of abdominal pain. Computed tomography shows swelling of the appendix, so diagnosis is …
jp, us
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2024
article
OpenAlex
Masaki Sano, Zhen Li, Akane Tsushima, Katsuhiko Kimura et autres
Abstract We present an annual-resolution, millennium-long tree-ring chronology for northern Japan. The chronology is based on 5309 measurements of tree-ring δ18O from 37 samples of Hiba arbor-vitae (Thujopsis dolabrata var. hondae). Although the exact geographical origin of 27 of the samples is …
jp
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2023
article
OpenAlex
Mizuka Kobayashi, Shiori Nakagawa, Toshio Nakamura, Takuo Tsuno
Rice bran contains an abundance of phytosterols. We have prepared phytosterol ester extract (PEE), which consists of a phytosterol ester and fatty acids made from the by-product of extracting oil from rice bran. PEE has been registered as a cosmetic ingredient in …
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2023
article
OpenAlex
Yuho Yamauchi, Zhou Jingxiu, Shiori Nakagawa, Yoshikazu Uchida et autres
Background: Rice bran contains various active ingredients that have attracted attention as materials for use in health foods and cosmetics. Vitamin E has beneficial antioxidant effects and are used in cosmetics. We have developed a method for producing Rice Vitamin E crude …
Accès ouvert
2022
article
OpenAlex
Fusa Miyake, Masataka Hakozaki, Katsuhiko Kimura, Fuyuki Tokanai et autres
Cosmogenic nuclides such as 14C from tree rings and 10Be and 36Cl from ice cores are excellent proxies for the past extremely large solar energetic particle (SEP) events, which are dozens of times larger than the largest SEP event in the history …
jp
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Accès ouvert
2022
preprint
OpenAlex
Mizuka Kobayashi, Shiori Nakagawa, Toshio Nakamura, Takuo Tsuno
Rice bran contains an abundance of phytosterols. We have developed “Riceterol EsterTM” (RSE), which consists of a phytosterol ester and fatty acids made from the by-product of extracting oil from rice bran. RSE has been registered as a cosmetic ingredient in rice …
Accès ouvert
2022
preprint
OpenAlex
Genki INOUE, Eisuke Honda, Keisuke Ito, Ijin Kang et autres
Abstract We studied Holocene paleolimnological changes inferred from multi-proxy data set of CNS elements, biomarkers and microscopic observation of microalgae and cyanobacteria in sediment cores from Rundvågshetta lakes (Maruwanminami-ike and Maruwan o-ike) in the Soya Coast region of East Antarctica, along with …
jp, cn
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Accès ouvert
2022
article
OpenAlex
Yosuke Mihara, Kinji Kamiya, Masaki Azuma, Atsushi Maema et autres
症例は52歳,女性.胃癌(L-post,0-IIc,sig,pT1aN0M0,Stage Ia)に対して腹腔鏡下幽門側胃切除術(D1+郭清)を施行した.術後11カ月の造影CTで肝S4に造影効果に乏しい境界明瞭な16mmの腫瘤性病変を認めた.MRIでは肝転移が疑われたが,PET-CTでは同部位に集積は認められなかった.術後肝転移を疑い,肝部分切除の方針となった.術中に腫瘤の横行結腸浸潤を認め,肝部分切除術,胆嚢摘出術に加えて横行結腸部分切除術を行った.病理組織学的検査で胃癌由来の印環細胞癌を認めず,免疫染色と遺伝子解析の結果,腸間膜由来のデスモイド腫瘍と診断された.術後7日で退院となり,術後24カ月の現在も再発なく生存中である.デスモイド腫瘍はMRIやPET-CTなどの画像による診断が難しい.また,遺伝子解析が他の悪性腫瘍との鑑別に有用である.
jp
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