John McCafferty

NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease

Eilíse M. Ryan, Pranvera Sadiku, Patrícia Coelho, Emily Watts et autres

Abstract Rationale Chronic obstructive pulmonary disease (COPD) is a disease characterized by persistent airway inflammation and disordered macrophage function. The extent to which alterations in macrophage bioenergetics contribute to impaired antioxidant responses and disease pathogenesis has yet to be fully delineated. Objectives …

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Scientific Business Abstracts of the 113th Annual Meeting of the Association of Physicians of Great Britain and Ireland

Tessa Cacciottolo, A Perikari, Agatha van der Klaauw, Elana Henning et autres

Biography Tessa M. Cacciottolo graduated from the University of Malta Medical School, then moved to the UK to further her clinical training in general medicine, gastroenterology and hepatology. During this time she became interested in the interface between liver disease and metabolism. …

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S129 Indwelling pleural catheter versus talc pleurodesis in adults with malignant pleural effusion: a systematic review and meta-analysis

S Bonello, John McCafferty

Background Malignant pleural effusion (MPE) is an increasingly common condition. It can cause significant distress to patients and negatively impact their quality of life. Indwelling pleural catheters (IPC) have been widely used in the management of MPE over the years, and have …

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Book Review: Principles of Forensic Ballistics

John McCafferty