Si-Yao Xiao

Fei Wei formula attenuates pulmonary fibrosis by inhibiting lactate-driven endothelial mesenchymal transition via its target of HSP90ab1

Jin-Min Gu, Shenglan Wang, Shunan Zhang, Si-Yao Xiao et autres

BACKGROUND: Fei Wei formula (FW) has been integrated into clinical practice, demonstrating significant therapeutic efficacy for idiopathic pulmonary fibrosis (IPF). However, its underlying mechanism remains unclear. Pulmonary endothelial cells are a partial source of fibroblasts through endothelial mesenchymal transition (EndoMT), which contributes …

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Lu’e Biyan Formula for Treatment of Allergic Rhinitis Patients with Fei (Lung)-Qi Deficiency-Coldness Syndrome: A Randomized, Double Blind, and Placebo-Controlled Trial

Mingyue Jia, Meiyi Zhang, Si-Yao Xiao, Yang Yu et autres

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A clinical predictive model for the long-term survival of progressive fibrosis interstitial lung disease patients

Jin-Min Gu, Si-Yao Xiao, Botao Chen, Weichao Li et autres

Background: In patients with chronic fibrosing interstitial lung disease (ILD), some may develop a progressive fibrosing (PF) phenotype, which presents as rapid progression and often results in poor clinical outcomes. Objective: The objective of this study was to construct and test a …

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Effect of Chinese herbal medicine (CHM) as an adjunctive therapy in distinct stages of patients with COVID-19: A systematic review and meta-analysis

Jin-Min Gu, Shu-Nan Zhang, Si-Yao Xiao, Mingyue Jia et autres

BACKGROUND: The pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of infected cases and deaths worldwide. Clinical practice and clinical trials in China suggested that integrated Chinese herbal medicine (CHM) and …

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Risk factors for progression of pulmonary fibrosis: a single-centered, retrospective study

Jiajia Fan, Jin-Min Gu, Si-Yao Xiao, Mingyue Jia et autres

Objective This study aimed to identify clinical characteristics associated with the prevalence of progressive pulmonary fibrosis (PPF) in interstitial lung disease (ILD) and to develop a prognostic nomogram model for clinical use. Methods In this single-centered, retrospective study, we enrolled ILD patients …

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[Impact of extended-spectrum β-lactamase on clinical outcome and medical cost in patients with bloodstream infection due to Klebsiella pneumoniae].

J Q Li, Chenqi Tang, H Wang, S Z Ji et autres

OBJECTIVE: To evaluate the impact of extended-spectrum β-lactamase (ESBL) on clinical outcome and medical cost in patients with bloodstream infection (BSI) due to Klebsiella pneumoniae. METHODS: A retrospective study was conducted in patients admitted into Changhai Hospital between January 2013 and December …

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