Gupta Pp

Concepts, types, and treatment strategies for neurodegenerative disorders

Rafquat Rana, Srishty Jaiswal, Mitali Sethi, Shourya Tripathi et autres

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Emphasizing mitochondrial dysfunction and autophagy in the treatment of neurological disorders

Srishty Jaiswal, Shourya Tripathi, Rafquat Rana, Mitali Sethi et autres

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Antiallergic activity of alkyl substituted pyrazolo[3, 4-d]pyrimidine (compound 88-765).

Gupta Pp, Srimal Rc, Kamlakar Avasthi, Neeraj Kumar Garg et autres

Compound 88-765 (4-amino-6-methylthio-1-(2', 2'-diethoxyethyl)-1 H-pyrazolo[3, 4-d]pyrimidine) has shown potent antiallergic activity in experimental models. The compound inhibited the passive cutaneous anaphylaxis (PCA) reaction in rats in dose-dependent manner (5-100 mg/kg, po) by 47 to 87%. In mice it inhibited PCA by 78% …

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Effects of peroxidized oil on the development of experimental atherosclerosis in rabbits.

J. K. Gulati, Gupta Pp, Soni Gl, SHYAMA VADHERA et autres

Ingestion of peroxidized oil under hypercholesterolemic dietary conditions resulted in a number of biochemical and pathological changes in rabbits. Total lipids, cholesterol and glyceride levels of plasma, liver and aorta were significantly higher in peroxidized oil fed rabbits, compared to the ones …

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Characterization of dopamine receptors involved in central thermoregulation in rabbits.

Srivastava Ak, Srivastava Yp, Gupta Pp, Verma Rb

Intracerebroventricularly administered dopamine produced dose dependent hyperthermia in rabbits. Haloperidol, a D1 receptor blocker produced consistent hypothermia, whereas D2 receptor blocker metoclopramide produced hyperthermia, pretreatment with haloperidol competitively blocked the hyperthermic response of dopamine. Pretreatment with metoclopramide augmented the onset and peak …

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Effect of garlic on serum cholesterol and electrocardiogram of rabbit consuming normal diet.

Gupta Pp, P Khetrapal, CL Ghai

Effect of garlic on experimental atherosclerosis in rabbits.

Mand Jk, Gupta Pp, Soni Gl, Rambir Singh

Cirrhosis of the liver in rabbits induced by a high cholesterol diet--an experimental model.

Gupta Pp, Tandon Hd, Ramalingaswami

Liver changes in pigs fed a diet low in protein and high in fat and cholesterol.

Gupta Pp, Tandon Hd, Ramalingaswami

Cysts in the cardiac valves of swine.

Gupta Pp