Matilde De Simone

Pulmonary metastasectomy for recurrent hepatocellular carcinoma after liver transplantation: A therapeutic challenge

Alessandro Pardolesi, Michele Ferrari, Giovanni Leuzzi, Edoardo Ceruti et autres

Recurrence of hepatocellular carcinoma remains the leading cause of mortality after liver transplantation (LT), with the lungs representing the most frequent extrahepatic site. This review evaluates the role of pulmonary metastasectomy in carefully selected LT recipients, with a focus on patient selection …

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Beyond survival: Pain as the main determinant of long-term quality of life after thoracic trauma surgery

Federico Raveglia, Sara Degiovanni, Luca Bertolaccini, Andrea Cara et autres

BACKGROUND Thoracic trauma is a major cause of trauma-related morbidity and mortality, often resulting from blunt mechanisms. While advances in acute management have improved short-term outcomes, long-term results-particularly health-related quality of life (QoL) after chest wall surgery-remain poorly defined. Identifying factors influencing …

Minimally invasive surgical approach for slipping rib syndrome: A case report

Francesca Spinelli, Francesco Petrella, Andrea Cara, Enrico Cassina et autres

BACKGROUND: Slipping rib syndrome (SRS) is caused by abnormal subluxation of floating ribs, resulting in chronic pain and possible tissue damage. Its prevalence is often overlooked, as it shares symptoms with other musculoskeletal conditions, and is more common in young females and …

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The Role of Epithelial–Mesenchymal Transition in Malignant Pleural Mesothelioma: From Pathogenesis to Diagnosis and Treatment

Dimitrios E. Magouliotis, Fabrizio Minervini, Ugo Cioffi, Matilde De Simone et autres

Malignant pleural mesothelioma (MPM) is an aggressive cancer of the pleural lining, primarily associated with asbestos exposure. Despite advancements in multimodal treatment, patient survival remains poor. Epithelial-mesenchymal transition (EMT) has emerged as a crucial process driving MPM pathogenesis, metastasis, and resistance to …

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Brain Imaging in Patients with Non-Small Cell Lung Cancer—A Systematic Review

Nóra Mayer, Laura Boschetti, Marco Scarci, Ugo Cioffi et autres

Background: Lung cancer frequently metastasizes to the brain, liver, and adrenal glands with a significant negative prognostic impact on overall survival and quality of life (QoL). To optimize treatment and prognosis, adequate staging with the detection of distant metastases is crucial. The …

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New paradigm of oral rehydration in patients affected by irritable bowel syndrome with chronic diarrhea

Marco Chiarelli, Matilde De Simone, Gerardo Cioffi, Ugo Cioffi

Irritable bowel syndrome with diarrhea is a very frequent clinical condition characterized by disabling intestinal symptoms. This disease presents with daily abdominal pain for at least 3 months related to defecation and associated with a change in the frequency of bowel movements …

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Vats lobectomy for lung cancer. What has been the evolution over the time?

Emanuela Cecconi, Giuseppe Mangiameli, Matilde De Simone, Ugo Cioffi et autres

Video assisted thoracic surgery (VATS) lobectomy is the treatment of choice for early-stage lung cancer. It is safe and effective compared to open surgery, as demonstrated by a large body of scientific evidence over the last few decades. VATS lobectomy's evolution was …

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Editorial on research topic: Surgery and COVID-19 in oncologic patients: What does the recent coronavirus pandemic taught us?

Ugo Cioffi, Marco Chiarelli, Alberto Testori, Matilde De Simone et autres

EDITORIAL article Front. Surg., 10 January 2023Sec. Surgical Oncology Volume 9 - 2022 | https://doi.org/10.3389/fsurg.2022.1081959

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Stapled Transanal Rectal Resection (Starr) in the Treatment of Obstructed Defecation: A Systematic Review

Lorenzo Ripamonti, Angelo Guttadauro, Giulia Lo Bianco, Maria Rennis et autres

Obstructed defecation syndrome (ODS) is a form of constipation that influences the quality of life in most patients and is an important health care issue. In 2004 Longo introduced a minimal invasive trans-anal approach known as Stapled Trans-Anal Rectal Resection (STARR) in …

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Small Bowel Intussusception Due to Rare Cardiac Intimal Sarcoma Metastasis: A Case Report

Marco Chiarelli, Mauro Zago, Fulvio Tagliabue, Morena Burati et autres

Background: Intimal sarcomas are rare malignant mesenchymal tumors arising from the heart and large blood vessels. Their intraluminal growth leads to vascular obstructive symptoms and peripheral neoplastic embolization. Direct infiltration of the lungs or metastases to the pulmonary system, occur in 40% …

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Editorial: Surgery and COVID-19: Which Strategies to Apply in Oncologic Patients

Ugo Cioffi, Michele M. Ciulla, Matilde De Simone, Marco Scarci et autres

Ugo Cioffi1*Michele M. Ciulla2Matilde De Simone1Marco Scarci3Alberto Testori4Federico Raveglia3Marco Chiarelli5

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Standardization of Procedures to Contain Cost and Reduce Variability of Care After the Pandemic

Federico Raveglia, Riccardo Orlandi, Arianna Rimessi, Fabrizio Minervini et autres

The coronavirus disease 2019 (COVID-19) pandemic has changed many aspects of our private and professional routine. In particular, the lockdowns have severely affected the entire healthcare system and hospital activities, forcing it to rethink the protocols in force. We suggest that this …

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