Marina Cao

Identification of plasma biomarkers in lipid metabolism for accurate prediction of Alzheimer’s disease

Xiaohui Luo, Longhao Jia, Jixin Cao, Qihao Guo et autres

Metabolomics may reveal non-invasive biomarkers for early diagnosis in Alzheimer's disease (AD) and provide new insights into the disease mechanisms to develop effective treatments. Here, we comprehensively analyzed the blood plasma metabolomes from a Chinese cohort of 447 individuals, including 188 AD, …

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An integrative multi-omics approach identifies microbiome alterations linked to pathological and behavioral features in autism spectrum disorder

Kai Mi, Marina Cao, Lingli Zhang, Qianlong Zhang et autres

This study employs a multi-omics approach to investigate the gut-brain axis in 326 children with autism spectrum disorder (ASD) and 169 typically developing (TD) controls, aged 0-10 years. By analyzing neuroimaging, gut microbiome, and plasma metabolome data, we find that microbial features …

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Neuropsychiatric Symptoms in Huntington’s Disease: A Case Report on Manic and Psychotic Features Huntington’s disease (HD)

S. Buyo Lagares, A. Picallo Vieito, Marina Cao, Mar Iglesias et autres

Introduction Huntington’s disease (HD) is a hereditary neurodegenerative disorder marked by progressive declines in motor, cognitive, and psychiatric functions. This case report presents a 45-year-old female patient with HD who displayed significant manic symptoms, which later evolved into acute psychosis. Notably, her …

Chronic diarrhea related to neuroblastoma: the important role of vasoactive intestinal peptide in tumor pathology and survival

Marina Cao, Kun Zhang, Jing Guo, Fang Dong et autres

To analyze the correlation between vasoactive intestinal peptide (VIP) protein expression in neuroblastoma (NB) tumors and NB clinical features and prognosis. Clinical data were collected from 91 patients with NB aged < 18 years who underwent tumor resection at the Shengjing Hospital …

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A Novel Method for Mitochondrial Membrane Potential Detection in Heart Tissue Following Ischemia-reperfusion in Mice

Chao Yin, Le Pan, Ying Wang, Marina Cao et autres

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The Effects of an Integrated Exercise Intervention on the Attenuation of Frailty in Elderly Nursing Homes: A Cluster Randomized Controlled Trail

Tianze Liu, Chaojie Wang, Jiao Sun, W. Chen et autres

OBJECTIVES: The frail elderly have an increased risk of frailty because of reduced physical activity, cognitive ability and quality of life. This study aims to evaluate the effects of integrated exercise intervention on the attenuation of frailty in elderly nursing home residents. …

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Early versus conventional nutritional intervention in head and neck cancer patients before radiotherapy: Benefits of a fast track circuit

Marcos González, Rosângela Correa Villar, Manuel Alfaro Sifontes, Ernesto A. Gómez et autres

Online cognitive bias modification and motivational interviewing in Chinese smokers: a single-case experimental study

Shi Wu Wen, Helle Larsen, Marina Cao, P. Kong et autres

Background: Empirically validated smoking interventions are urgently needed in China. Relatively automatic action tendencies toward smoking-related cues have been related to smoking behavior. Re-training of addiction-related action tendencies using Cognitive Bias Modification (CBM) has been shown promising clinical effects, when participants are …

Neuropsychiatric Symptoms and Interleukin-6 Serum Levels in Acute Stroke

Gianfranco Spalletta, Luca Cravello, Francesca Imperiale, Francesca Salani et autres

The role of interleukin-6 (IL-6) as a risk factor for developing depressive symptoms, neuropsychological impairment, and related functional and neurological symptom severity during the acute phase of ischemic stroke is still underexplored. Here, the authors assessed this issue, in 48 patients without …

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Disease Outcome, Alexithymia and Depression are Differently Associated with Serum IL-18 Levels in Acute Stroke

Paola Bossù, Francesca Salani, Claudia Cacciari, Livio Picchetto et autres

Stroke has been shown to lead to depressive disorders, anxiety disorders and other emotional consequences. Although the cause of these disorders is a subject of debate, stroke has clearly been shown to lead to the production of pro-inflammatory cytokines, which we hypothesized …

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CADASIL presenting as status migrainosus and persisting aura without infarction

Simona Sacco, Maurizia Rasura, Marina Cao, Alessandro Bozzao et autres

Different types of migraine have been reported in 20-40% of patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). We describe a novel migrainous manifestation of CADASIL consisting in status migrainosus and persistent aura without infarction. The symptoms resolved …

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Long-term Prognosis After a Minor Stroke

Massimiliano Prencipe, Franco Culasso, Maurizia Rasura, A. Anzini et autres

BACKGROUND AND PURPOSE: Determinants of long-term outcome are not well defined in minor stroke patients. This study aims to evaluate which factors are independent long-term predictors of death and major stroke recurrence in a cohort of minor ischemic strokes. METHODS: A cohort …

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