A. J. A. Terzis

PROFESSIONAL EXPERIENCE (CONTINUED)

J. Gupchup, Dorothy Stano Carlson, Raluca Musaloiu-E., A. Szalay et autres

Transplants for Glioblastoma

Jian Wang, A. J. A. Terzis, Karen Saida Aboody, Per Øyvind Enger et autres

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Angiogenesis-independent tumor growth mediated by stem-like cancer cells

Per Øystein Sakariassen, Lars Prestegarden, Jian Wang, Kai-Ove Skaftnesmo et autres

In this work, highly infiltrative brain tumors with a stem-like phenotype were established by xenotransplantation of human brain tumors in immunodeficient nude rats. These tumors coopted the host vasculature and presented as an aggressive disease without signs of angiogenesis. The malignant cells …

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Protein Disulfide Isomerase Expression Is Related to the Invasive Properties of Malignant Glioma

Dorota Goplen, Jian Wang, Per Øyvind Enger, Berit B. Tysnes et autres

By serial transplantation of human glioblastoma biopsies into the brain of immunodeficient nude rats, two different tumor phenotypes were obtained. Initially, the transplanted xenografts displayed a highly invasive phenotype that showed no signs of angiogenesis. By serial transplantation in animals, the tumors …

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Invasion and metastasis

Rolf Bjerkvig, A. J. A. Terzis, Sverre Jarl Mørk

The location of PTEN on chromosome 10q23 is important, because this is a genomic region that suffers loss of heterozygosity in many human cancers (Cantley and Neel, 1999). Although early genetic studies did not find any genetic heterogeneity among BRRS and CS …

Cell therapies for glioblastoma

A. J. A. Terzis, Simone P. Niclou, Uroš Rajčević, Claude Danzeisen et autres

Malignant gliomas, including the most devastating type, glioblastoma multiforme (GBM), are characterised by their local growth and aggressive infiltration of the normal brain. GBMs result in a profound disability, leading to death in almost all cases. There has been little improvement in …

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Erratum: The origin of the cancer stem cell: current controversies and new insights

Rolf Bjerkvig, Berit B. Tysnes, Karen Saida Aboody, Joseph Najbauer et autres

The origin of the cancer stem cell: current controversies and new insights

Rolf Bjerkvig, Berit B. Tysnes, Karen Saida Aboody, Joseph Najbauer et autres

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Distribution patterns of the anti-angiogenic protein ADAMTS-1 during rat development

W. C. Gunther, Kai-Ove Skaftnesmo, Hans Arnold, Rolf Bjerkvig et autres

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Bacitracin inhibits glioma cell migration and invasion in vitro.

Dorota Goplen, Jian Wang, Berit B. Tysnes, A. J. A. Terzis et autres

3773 By serial transplantation of human glioblastoma biopsies in nude rats two different tumor phenotypes are obtained; one that is highly invasive and one that is predominantly angiogenic. Using a global proteomics approach on the phenotypes, we identified a number of unique …

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Cryopreservation of Alginate-Encapsulated Recombinant Cells for Antiangiogenic Therapy

Vidar Stensvaag, Tomasz Furmanek, K. Lønning, A. J. A. Terzis et autres

The potential benefit of continuous local administration of antiangiogenic proteins to CNS tumors in vivo has recently been demonstrated using endostatin-producing recombinant cells encapsulated in alginate beads. Due to the treatment potential of transplanted alginate-encapsulated cells producing therapeutic proteins, we describe a …

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Molecular approaches to brain tumour invasion

W. G�nther, Kai Ove Skaftnesmo, Hans Arnold, A. J. A. Terzis

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