Grace Hattersley

A prospective cohort study evaluating disease-specific mortality in patients with early-stage Barrett’s esophagus-related neoplasia following endoscopic therapy

Sally Pan, Grace Hattersley, Vijayendran Sujendran, Inés Modolell et autres

BACKGROUND: Endoscopic eradication therapy (EET) for Barrett's esophagus (BE)-related neoplasia is safe and effective in the short term, however there are limited data on long-term outcomes. We aim to provide further evidence on the long-term efficacy of EET in patients with BE-related …

gb, pt (code pays fourni par la source)

Cancer Burden on Piecemeal Endoscopic Resection of Early Adenocarcinoma in Barrett's Oesophagus Correlates With the Risk of Neoplastic Recurrence

Grace Hattersley, Andreas V. Hadjinicolaou, Andrea Sorge, Daniel Conceição et autres

BACKGROUND AND STUDY AIMS: Endoscopic resection (ER) is curative for early-stage oesophageal adenocarcinoma (OAC) without high-risk features. Piecemeal endoscopic mucosal resection (pEMR) prevents assessment of lateral margins, complicating risk estimation for neoplastic recurrence. We investigated the risk factors for residual and recurrent …

gb, it, pt (code pays fourni par la source)

Cancer burden on piecemeal endoscopic resection of early adenocarcinoma in Barrett’s oesophagus correlates with the risk of neoplastic recurrence

Grace Hattersley, Andreas V. Hadjinicolaou, Andrea Sorge, Daniel Conceição et autres

Abstract Background and study aims Endoscopic resection (ER) is curative for early-stage oesophageal adenocarcinoma (OAC) without high-risk features. Piecemeal endoscopic mucosal resection (pEMR) prevents assessment of lateral margins, complicating risk estimation for neoplastic recurrence. We investigated risk factors for residual and recurrent …

pt, gb, it (code pays fourni par la source)

O76 Prevalence of premalignant upper GI conditions and associated risk factors in upper GI endoscopy population: data from the PROSPERO study

Andreas V. Hadjinicolaou, Inés Modolell, Shriya Vishwanathan, Grace Hattersley et autres

gb (code pays fourni par la source)

The impact of metformin on placental ageing in humans and mice

Grace Hattersley, Yang Liu, Jane L. Tarry‐Adkins, Antonia Hufnagel et autres

Abstract Placental ageing refers to the physiological accumulation of a senescent phenotype over a healthy pregnancy. In pregnancies affected by complications such as pre‐eclampsia and fetal growth restriction, placental ageing is notably accelerated and observed at an earlier gestational age. Metformin is …

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547. DISEASE SPECIFIC MORTALITY OF EARLY-STAGE ESOPHAGEAL NEOPLASIA IN BARRETT’S ESOPHAGUS TREATED WITH ENDOSCOPIC THERAPY

Sally Pan, Grace Hattersley, Vijayendran Sujendran, Inés Modolell et autres

Abstract Background High-grade dysplasia (HGD) and intramucosal (T1a) esophageal adenocarcinoma (EAC) are indication for endoscopic eradication therapy (EET) with endoscopic resection (ER) and/or radiofrequency ablation (RFA). The goal of the endoscopic therapy is to prevent progression to advanced EAC and cure the …

gb (code pays fourni par la source)

356. TUMOUR BURDEN CORRELATES WITH THE RISK OF RECURRENCE AFTER PIECEMEAL ENDOSCOPIC RESECTION OF EARLY-STAGE ADENOCARCINOMA IN BARRETT’S OESOPHAGUS

Grace Hattersley, Andreas V. Hadjinicolaou, Andrea Sorge, Daniel Conceição et autres

Abstract Background Endoscopic resection (ER) is curative for Barrett’s oesophagus-related early-stage oesophageal adenocarcinoma (EAC) without high-risk features, such as lymphovascular invasion (LVI), positive margins (R1), and deep submucosal invasion (T1bsm2-3). Piecemeal endoscopic mucosal resection (pEMR), often used for lesions larger than 15mm, …

gb, it (code pays fourni par la source)

O5 Tumour burden correlates with the risk of recurrence after piecemeal endoscopic resection of early-stage adenocarcinoma in Barrett’s oesophagus

Grace Hattersley, Andreas V. Hadjinicolaou, Andrea Sorge, Daniel Conceição et autres

gb, it (code pays fourni par la source)