Kai He

FgNR gene regulates growth, pathogenicity, and fungicide sensitivity in Fusarium graminearum

Bing Lin Hu, Xuhao Guo, Jia Jiang, Le Qian et autres

cn (code pays fourni par la source)

Ursolic Acid Inhibits Breast Tumor Growth and Angiogenesis through Suppression the Expression of Multiple Adhesion Factors

Xing Ji, Kai He

Ursolic acid (UA), a natural pentacyclic triterpenoid, has been reported to exert anti-cancer and anti-angiogenic effects. However, its role in suppressing breast cancer metastasis through modulation of endothelial function and tumor microcirculation remains to be fully elucidated. In this study, we investigated …

cn (code pays fourni par la source)

Toltrazuril inhibits Toxoplasma gondii by potentially targeting pyrimidine metabolism

Yan An, Kai He, Min Xiong, Xu Wang et autres

cn (code pays fourni par la source)

Optimizing nitrogen input to control health and environmental risks in Chinese vegetable production

Xingshuai Tian, Huifang Zheng, Yulong Yin, Qingsong Zhang et autres

Given the health and environmental risks of excessive nitrogen (N) use, optimizing N input is crucial for sustainable vegetable production in China. We compiled a comprehensive database to examine the relationship between N input, vegetable yield, nitrate content, and reactive N (Nr) …

cn (code pays fourni par la source)

Corrigendum to “A novel ENTH domain-containing protein TgTEPSIN is essential for structural maintenance of the plant-like vacuolar compartment and bradyzoite differentiation in toxoplasma gondii” [Int. J. Biol. Macromol. 300 (2025) 140–311]

Kai He, Rui-Bin Wu, Yan An, Xianyong Liu et autres

cn (code pays fourni par la source)

A novel ENTH domain-containing protein TgTEPSIN is essential for structural maintenance of the plant-like vacuolar compartment and bradyzoite differentiation in toxoplasma gondii

Kai He, Rui-Bin Wu, Yan An, Xianyong Liu et autres

cn (code pays fourni par la source)

Prenatal p25-activated Cdk5 induces pituitary tumorigenesis through MCM2 phosphorylation-mediated cell proliferation

Yingwei Huang, Qi‐Qi Wang, Weiwei Zhou, Yawei Jiang et autres

Aberrant expression of cyclin-dependent kinase 5 (Cdk5) has been reported in pituitary adenomas. However, the role of Cdk5 in the tumorigenesis remains unclear. We show that prenatal p25-activated Cdk5 phosphorylates minichromosome maintenance protein 2 (Mcm2), enhancing minichromosome maintenance (MCM) family proteins and …

cn, us (code pays fourni par la source)

The estimation method is the primary source of uncertainty in cropland nitrate leaching estimates in China

Xingshuai Tian, Huitong Yu, Jiahui Cong, Yulong Yin et autres

Cropland nitrate leaching is the major nitrogen (N) loss pathway, and it contributes significantly to water pollution. However, cropland nitrate leaching estimates show great uncertainty due to variations in input datasets and estimation methods. Here, we presented a re-evaluation of Chinese cropland …

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Transcriptional dynamics of Fusarium pseudograminearum under high fungicide stress and the important role of FpZRA1 in fungal pathogenicity and DON toxin production

Jia Jiang, Kai He, Xinyu Wang, Yuan Zhang et autres

cn (code pays fourni par la source)

TBC9, an essential TBC-domain protein, regulates early vesicular transport and IMC formation in Toxoplasma gondii

Ming Sun, Tao Tang, Kai He, Shaojun Long

Apicomplexan parasites harbor a complex endomembrane system as well as unique secretory organelles. These complex cellular structures require an elaborate vesicle trafficking system, which includes Rab GTPases and their regulators, to assure the biogenesis and secretory of the organelles. Here we exploit …

cn (code pays fourni par la source)

A Sarcocystidae-Specific striated fiber assemblin protein SFA5 is required for parasite division in Toxoplasma gondii

Yuebao Li, Xiaoyan Tang, Kai He, Hui Dong et autres

Abstract Apicomplexan encompass a variety of intracellular parasites responsible for significant diseases in humans and animals, such as malaria and toxoplasmosis. Among these, Toxoplasma gondii (T. gondii) serves as an exemplary organism for understanding the intricate biological characteristics of the phylum. At …

cn, us (code pays fourni par la source)

The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival

Hui Dong, Jiong Yang, Kai He, Wen-Bin Zheng et autres

The apicoplast is a four-membrane plastid found in the apicomplexans, which harbors biosynthesis and organelle housekeeping activities in the matrix. However, the mechanism driving the flux of metabolites, in and out, remains unknown. Here, we used TurboID and genome engineering to identify …

cn, ch, us, gb (code pays fourni par la source)