S Gasser

Adenosquamous Carcinoma of the Lung: Survival, Radiologic Findings, PD-L1, and Driver Mutations

Oliver Illini, Hannah Fabikan, Eva Fischer, Anna Sophie Lang-Stöberl et autres

Background: Adenosquamous carcinoma of the lung (ASC) is a rare non-small-cell lung cancer (NSCLC) subtype combining components of squamous cell carcinoma (SCC) and adenocarcinoma (AC). Data on ASC, particularly in Caucasian populations, are limited. Methods: We reviewed clinicopathological and radiological characteristics of …

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Feasibility, Clinical Potential, and Limitations of Trans-Burr Hole Ultrasound for Postoperative Evaluation of Chronic Subdural Hematoma: A Prospective Pilot Study

Stefan Aspalter, Matthias Gmeiner, S Gasser, Michael Sonnberger et autres

BACKGROUND AND OBJECTIVES: Chronic subdural hematoma (CSDH) is commonly managed through burr hole surgery. Routine follow-up using computed tomography (CT) imaging is frequently used at many institutions, contributing to significant radiation exposure. This study evaluates the feasibility, safety, and reliability of trans-burr …

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Twenty-year trends in the prevalence of modifiable cardiovascular risk factors in young acute coronary syndrome patients hospitalized in Switzerland

Thabo Mahendiran, André Hoepli, Fabienne Foster‐Witassek, Hans Rickli et autres

AIMS: Modifiable cardiovascular risk factors (RFs) play a key role in the development of coronary artery disease. We evaluated 20-year trends in RF prevalence among young adults hospitalized with acute coronary syndromes (ACS) in Switzerland. METHODS AND RESULTS: Data were analysed from …

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Twenty-Year Trends in the Incidence and Outcome of Cardiogenic Shock in AMIS Plus Registry

Lukas Hunziker, Dragana Radovanović, Raban V. Jeger, Giovanni Pedrazzini et autres

BACKGROUND: Long-term trends of the incidence and outcome of cardiogenic shock (CS) patients are scarce. We analyze for the first time trends in the incidence and outcome of CS during a 20-year period in Switzerland. METHODS AND RESULTS: The AMIS (Acute Myocardial …

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Fatale immunmediierte organisierende Pneumonie unter Pembrolizumab – Therapie eines pulmonalen Adenokarzinoms

S Gasser, Dagmar Krenbek, Maximilian Johannes Hochmair

Einleitung Pembrolizumab (Keytruda ® ) ist ein Immun-Checkpoint-Inhibitor, der zur Therapie des nicht kleinzelligen Lungenkarzinoms (NSCLC) bei spezifischer genetischer Mutation („Programmierter-Zelltod-Rezeptor 1“, PD-1-Positivität) zugelassen ist (Sul J, Blumenthal GM, Jiang X et al. Oncologist 2016; 21: 643 – 650). Eine der relevanten …

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Improvement of Quality of Life and Mental Recovery after Left Ventricular Assist Device Implantation compared to Heart Transplantation

Markus Jan Barten, S Gasser, Alexander M. J. Bernhardt, Connor Buchholz et autres

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Hybrid Approach for Branch Pulmonary Artery Stenosis in Congenital Heart Disease

Maria von Stumm, S Gasser, Connor Buchholz, Götz Müller et autres

All articles of this category Objectives: Branch pulmonary artery (BPA) stenosis is a common finding in patients with congenital heart disease (CHD), particularly in patients after repair of tetralogy of Fallot (ToF)/pulmonary atresia (PA). In this subset of patients ~10% require re-intervention …

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Quality of Life and Mental Recovery after Left Ventricular Assist Device Implantation Compared to Heart Transplantation

S Gasser, Alexander M. J. Bernhardt, Meike Rybczynski, Hanno Grahn et autres

All articles of this category Background: Due to the shortage of organ donors the number of continuous flow left ventricular assist device (cfLVAD) implantation is increasing. The aim of this study was to compare early quality of life (QoL) and mental recovery …

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A Novel Technique to Repair Absence of Right Pulmonary Artery

Maria von Stumm, S Gasser, Connor Buchholz, Arlindo Almeida Riso et autres

All articles of this category Objectives: Unilateral isolated absence of a pulmonary artery (UAPA) is a rare congenital lesion, which can lead to pulmonary hypoplasia and pulmonary hypertension. To avoid these complications, early surgical repair of UAPA is recommended. Surgical approaches include …

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P3.03-024 Real-Life Experience and Clinical Characterization of BRAF V600E Mutation in Austrian NSCLC Patients

Sophia Schwab, Ulrike Setinek, Dagmar Krenbek, Stefan Watzka et autres

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[PP.30.25] EFFECT OF MAGNESIUM DEPRIVATION ON HYPERTENSION RELATED GENE EXPRESSION PROFILES IN HUMAN HEART

Robert N. A. Gasser, Cornelia Ablasser, S Gasser

Objective: While we well understand that nutritional Mg2+-deprivation may lead to increased blood pressure and numerous cellular dysfunctions, the effects of extracellular Mg2+-concentrations on molecular pathways and processes has not been studied as yet. Characterising these Mg2+-dependent intracellular molecular pathways may well …

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[PP.20.04] CARDIOPROTECTIVE MODULATION OF T-CELL IMMUNITY BY ANTIHYPERTENSIVE SS-BLOCKER NEBIVOLOL DURING EXPERIMENTAL ISCHEMIA IN HUMAN MYOCARDIAL TISSUE

S Gasser, Klemens Ablasser, Robert N. A. Gasser

Objective: Recent experimental evidence suggests a crucial role of T-lymphocytes in the pathophysiology of myocardial injury. It has been indicated that a pro-inflammatory imbalance resulting from T-cell activation could be responsible for activating the inflammatory cascade ultimately responsible for cellular injury, left …

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