George Joseph

Nanobubbles in Bulk Solution and Electrosprayed Microdroplets Accelerate Chemical Reactions

Bincy Binny, George Joseph, André Venter

Abstract Bulk nanobubbles (NBs) are metastable gas-filled voids in solution, with diameters of nearly 200 nm that exhibit long lifetimes and large surface-to-volume ratios. Recent studies have shown that chemical reactions are significantly accelerated within sprayed microdroplets during electrospray ionization mass spectrometry …

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Nanobubble Formation by Flow Regime Switching Using a Tesla Valve

George Joseph, Bincy Binny, André Venter

High Resolution Image Download MS PowerPoint Slide Nanobubbles (NBs) are very small gas cavities in solution, and when their sizes reach diameters around 200 nm, they exhibit special qualities with widespread application. We introduce a novel, cost-effective method for the generation of …

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The Role of Nanobubbles in Protein Unfolding during Electrothermal Supercharging

George Joseph, Bincy Binny, André Venter

High Resolution Image Download MS PowerPoint Slide Nanobubbles (NBs) are tiny gas cavities with diameters around 200 nm that remain stable in solution due to their unique properties, including low buoyancy and negative surface charges. Ammonium bicarbonate (ABC) is an alternative buffer …

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Nanobubbles in Electrospray Ionization Mass Spectrometry

George Joseph, Bincy Binny, André Venter

High Resolution Image Download MS PowerPoint Slide Nanobubbles (NBs) are very small gas-filled cavities in solvents, and when their sizes reach diameters around 200 nm, they remain in solution for extended periods of time, featuring special chemical and physical properties. Here, we …

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Transparency, Ethics, and Scaling in the Cultivated Meat Industry

George Joseph

Hydrogen Is the Superior Nebulization Gas for Desorption and Electrospray Ionization

Bincy Binny, George Joseph, André Venter

High Resolution Image Download MS PowerPoint Slide A previous comparative study between helium and nitrogen as nebulizing and desolvation gases in electrospray ionization (ESI) and desorption electrospray ionization (DESI) found that the signal responses of compounds of varying sizes and polarities were …

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Limitations of current analytical reference methods to determine vitamins in foods: Challenges to support regulatory compliance and nutritional composition data

Erik J M Konings, Brendon D. Gill, Jette Jakobsen, George Joseph et autres

Foods are analysed for their vitamin content to support the verification of regulatory compliance or to generate food composition data. Many international reference methods for the analysis of vitamins in foods originate from the 1990s. Advances in nutrition science and analytical technology …

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OTT Platforms and the Movie Industry: Evolving Business Models

George Joseph

Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery

Mark Edwards, Gordon Forbes, Neil Walker, Dion Morton et autres

INTRODUCTION: Postoperative morbidity and mortality in patients undergoing major emergency gastrointestinal surgery are a major burden on healthcare systems. Optimal management of perioperative intravenous fluids may reduce mortality rates and improve outcomes from surgery. Previous small trials of cardiac-output guided haemodynamic therapy …

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Determination of Total Proteinogenic Amino Acids and Taurine by Pre-column Derivatization and UHPLC: Single Laboratory Validation, First Action Official Method SM 2019.09

George Joseph, Asha Varughese, Ann Daniel

BACKGROUND: A method has been developed and validated for selective, accurate, and precise determination of total proteinogenic amino acids and taurine from infant formula and adult/pediatric nutritional formulas (powders, ready-to-feed liquids, and liquid concentrates). The method was reviewed by the AOAC INTERNATIONAL …

Determination of Lutein, β-Carotene, and Lycopene in Infant Formula and Adult Nutritionals by Ultra-High Performance Liquid Chromatography: Collaborative Study, Final Action 2016.13 for β-Carotene and Lycopene Only

Gregory L Hostetler, Sylvie Bénet, Ruben Buis, Esther Campos-Giménez et autres

BACKGROUND: Lutein, β-carotene, and lycopene are among the most common carotenoids present in human milk and are frequently added to infant formula and adult nutritionals. OBJECTIVE: A collaborative study was conducted to assess the interlaboratory performance of AOAC Official MethodSM2016.13 for the …

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Vitamin B12 (cyanocobalamin) in Infant Formula Adult/Pediatric Nutritional Formula by Liquid Chromatography with Ultraviolet Detection: Collaborative Study, Final Action 2014.02

Ester Campos Giménez, Frédéric Martin, F Arella, J Austad et autres

To determine the repeatability and reproducibility figures of the AOAC First Action Official MethodSM 2014.02 (Vitamin B12 in Infant Formula and Adult/Pediatric Formula by Liquid Chromatography with UV Detection), a collaborative study was organized. Twenty-one laboratories located in 13 different countries agreed …

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