Attila Valikovics

Temporal Acoustic-Window Failure in Female Patients with Rheumatoid Arthritis: An Eight-Year Longitudinal Follow-Up Study

Attila Sas, Dávid Jónyer, Attila Valikovics, László Kostyál et autres

Background/Objectives: Rheumatoid arthritis (RA) is associated with increased cerebrovascular risk and altered bone metabolism. Transcranial Doppler (TCD) and transcranial color-coded duplex sonography (TCCD) require an adequate transtemporal acoustic window (TAW), which may be limited by temporal bone thickness and structure. Our previous …

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A Follow-Up Study of the Supraaortic and Intracranial Vessels, Cerebrovascular Reactivity, Brain Vascular Lesions and Atrophy in Patients with Rheumatoid Arthritis

Attila Sas, Dávid Jónyer, Attila Valikovics, László Kostyál et autres

Background/Objectives: Rheumatoid arthritis (RA) has been associated with accelerated atherosclerosis and cerebrovascular alterations. Our 2017 study compared 60 RA patients to healthy controls, assessing vascular, neurological, and cognitive parameters. The present study is a follow-up of these RA patients to evaluate disease …

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A prostata megmentheti az agyat? : Amikor a hátrány előnnyé válik

Ildikó Palló, Attila Valikovics, Csaba Oláh

Background and purpose: An unpleasant symptom of prostate hyperplasia is that older men get up to urinate at night. However, from the point of view of wake-up stroke, this can be an advantage, as they can detect their neurological deficit sooner due …

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Efficacy and Safety of Ticagrelor and Aspirin in Patients With Moderate Ischemic Stroke

Yongjun Wang, Yuesong Pan, Hao Li, Pierre Amarenco et autres

Importance: Prior trials of dual antiplatelet therapy excluded patients with moderate ischemic stroke. These patients were included in the Acute Stroke or Transient Ischaemic Attack Treated With Ticagrelor and ASA for Prevention of Stroke and Death (THALES) trial, but results have not …

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Ticagrelor Added to Aspirin in Acute Nonsevere Ischemic Stroke or Transient Ischemic Attack of Atherosclerotic Origin

Pierre Amarenco, Hans Denison, Scott Evans, Anders Himmelmänn et autres

Background and Purpose: Among patients with a transient ischemic attack or minor ischemic strokes, those with ipsilateral atherosclerotic stenosis of cervicocranial vasculature have the highest risk of recurrent vascular events. Methods: In the double-blind THALES (The Acute Stroke or Transient Ischemic Attack …

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Ticagrelor Added to Aspirin in Acute Ischemic Stroke or Transient Ischemic Attack in Prevention of Disabling Stroke

Pierre Amarenco, Hans Denison, Scott Evans, Anders Himmelmänn et autres

IMPORTANCE: Reduction of subsequent disabling stroke is the main goal of preventive treatment in the acute setting after transient ischemic attack (TIA) or minor ischemic stroke. OBJECTIVE: To evaluate the superiority of ticagrelor added to aspirin in preventing disabling stroke and to …

pt, fr, se, us, es, cn (code pays fourni par la source)

Safety and efficacy of GABAA α5 antagonist S44819 in patients with ischaemic stroke: a multicentre, double-blind, randomised, placebo-controlled trial

Hugues Chabriat, Claudio L. Bassetti, Ute C. Marx, Marie-Laure Audoli-Inthavong et autres

fr, ch, de (code pays fourni par la source)

Az előrehaladott Parkinson-kór jellemzői a klinikai gyakorlatban: az OBSERVE-PD vizsgálat eredményei és a magyarországi alcsoport elemzése

Annamária Takáts, Zsuzsanna Aschermann, László Vécsei, Péter Klivènyi et autres

BACKGROUND AND PURPOSE: The majority of patients with advanced Parkinson's disease are treated at specialized movement disorder centers. Currently, there is no clear consensus on how to define the stages of Parkinson's disease; the proportion of Parkinson's patients with advanced Parkinson's disease, …

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Assessment of cognitive function in female rheumatoid arthritis patients: associations with cerebrovascular pathology, depression and anxiety

Csaba Oláh, Zsófia Kardos, Mónika Andrejkovics, Enikő Szarka et autres

We assessed cognitive function of female rheumatoid arthritis (RA) patients and analyze the determinants, with special focus on cerebrovascular morphology. Sixty methotrexate (MTX-) or biologic-treated RA patients and 39 healthy controls were included in a cross-sectional study. Smoking habits, alcohol intake and …

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Implant for Augmentation of Cerebral Blood Flow Trial-1 (ImpACT-1). A single-arm feasibility study evaluating the safety and potential benefit of the Ischemic Stroke System for treatment of acute ischemic stroke

Dheeraj Khurana, Subhash Kaul, Dietmar Schneider, Attila Csányi et autres

BACKGROUND: The Ischemic Stroke System is a novel device designed to deliver stimulation to the sphenopalatine ganglion(SPG).The SPG sends parasympathetic innervations to the anterior cerebral circulation. In rat stroke models, SPG stimulation results in increased cerebral blood flow, reduced infarct volume, protects …

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Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

Ludwig Kappos, Amit Bar‐Or, Bruce Cree, Robert J. Fox et autres

ch, ca, us, gb, de, fr, be, nl (code pays fourni par la source)

Assessment of intracranial vessels in association with carotid atherosclerosis and brain vascular lesions in rheumatoid arthritis

Csaba Oláh, Zsófia Kardos, Mariann Sepsi, Attila Sas et autres

BACKGROUND: Stroke has been associated with rheumatoid arthritis (RA). We assessed patients with RA and healthy control subjects by transcranial Doppler (TCD), carotid ultrasonography and brain magnetic resonance imaging (MRI). METHODS: Altogether, 41 female patients with RA undergoing methotrexate (MTX) or biologic …

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