M Frankel

Abstract 398: Serum Magnesium Levels and Intraparenchymal Hemorrhage After Mechanical Thrombectomy

Sónia Batista, Xiaoyi Gu, M. Liu, Paulo N. Martins et autres

Purpose Experimental evidence suggests that magnesium plays a hemostatic role by enhancing activation of clotting factors, increasing platelet adhesion, and shortening coagulation times. Given its potential to reduce hemorrhagic complications, we investigated the association between baseline serum magnesium levels and risk of …

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EXPRESS: Global Impact of the COVID-19 Pandemic on Stroke Hospitalizations and Mechanical Thrombectomy Volumes.

Raul G. Nogueira, Mohamad Abdalkader, Muhammed M. Qureshi, M Frankel et autres

BACKGROUND The COVID-19 pandemic led to profound changes in the organization of health care systems worldwide. AIMS We sought to measure the global impact of the COVID-19 pandemic on the volumes for mechanical thrombectomy (MT), stroke, and intracranial hemorrhage (ICH) hospitalizations over …

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E-062 Impact of angiographic appearance of proximal middle cerebral artery occlusion on first pass reperfusion

Mahmoud Mohammaden, Diogo C Haussen, Leonardo Pisani, Alhamza R Al‐Bayati et autres

Background and Purpose The first pass effect (FPE) is a key predictor of clinical outcome after mechanical thrombectomy (MT) for large vessel occlusion stroke (LVOS). We aim to study the impact of initial angiographic appearance of middle cerebral artery (MCA) occlusion on …

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P-025 Off-hour presentation and outcomes in patients with large vessel occlusion after endovascular therapy: a matched case-control study

Jonathan A Grossberg, Mehdi Bouslama, Diogo C Haussen, M Frankel et autres

Background Patients who are admitted during off-hours (nights and weekends) are thought to have worse outcomes. This might be explained by delayed times to treatment. We sought to determine the effect of off-hour presentation on processes of care and outcomes at a …

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E-133 Body mass index and clinical outcomes in large vessel occlusion acute ischemic stroke after endovascular therapy: the obesity paradox

Jonathan A Grossberg, Mehdi Bouslama, Diogo C Haussen, M Frankel et autres

Background Obesity has been associated with increased morbidity and mortality in the general population. However, several reports have described lower mortality rates in overweight or obese patients as compared to normal weight ones. Investigations into this phenomenon, commonly described as the obesity …

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E-155 Endovascular therapy for large vessel occlusion acute stroke in nonagenarians versus octogenarians

Jonathan A Grossberg, Mehdi Bouslama, Diogo C Haussen, M Frankel et autres

Background Little is known on the outcomes of nonagenarians treated with endovascular therapy for acute large vessel occlusion stroke. It is unclear whether they have worse clinical outcomes than octogenarians. Methods We reviewed our prospectively collected endovascular database at a tertiary care …

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P-026 Cervical Carotid "Pseudo-Occlusion:" Intracranial Occlusions Masquerading as Extracranial Occlusions

Jonathan A Grossberg, Fabrício Bruno Cardoso, MDL Rebello, Diogo C Haussen et autres

Introduction The entity of internal carotid artery (ICA) “pseudo-occlusion,” where an occlusion of the intracranial ICA appears as an occlusion of the extracranial cervical ICA on computed-tomography angiography (CTA) or digital subtraction angiography (DSA) is more common than previously thought. We aim …

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O-020 A comparison of infarct volumes in patients with large vessel occlusions based on treatment modality: a retrospective analysis: Abstract O-020 Figure 1

S Rangaraju, Kumiko Owada, Alireza Noorian, Brenda A Glenn et autres

Introduction Intra-arterial (IA) therapy for large vessel occlusions (LVO) results in higher recanalization rates compared to intravenous (IV) thrombolysis. Recanalization after LVO is also a predictor of better clinical outcome. Whether IA therapy results in lower stroke infarct burden has not previously …

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Rapid change in prescribing behavior in hospitals participating in Get With the Guidelines- Stroke after release of the MATCH clinical trial results

M Frankel, Lee H. Schwamm, Gregg C. Fonarow, Liang Li et autres

Asymptomatic hemorrhagic transformation of cerebral infarction does not worsen long-term outcome

Richard Libman, Thomas Kwiakowski, Patrick D. Lyden, James C. Grotta et autres

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Intravenous thrombolysis for acute stroke

Patrick D. Lyden, J. Grotta, Steven R. Levine, John R. Marler et autres

Until recently there was no specific therapy for stroke, but the recent publication of the National Institute of Neurological Disorders and Stroke(NINDS) t-PA for Acute Stroke Trial presents the first effective, specific therapy for stroke.1 In considering whether to apply thrombolysis to …

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