Joanna Davies

628 Insights into pneumothorax in very low birth weight (VLBW) infants

Katie M. Morgan, Sara MM Yasrebi, RM Lenzini, Dajana Sabic et autres

The Impact of Vitamin D Deficiency on the Severity of Symptoms and Mortality Rate among Adult Patients with Covid-19: A Systematic Review and Meta-Analysis

Maisa Hamed Al Kiyumi, Sanjay Kalra, Joanna Davies, Atul Kalhan

Introduction: We aimed to study the prevalence of vitamin D deficiency (VDD) in patients with COVID-19 infection and evaluate the impact of vitamin D levels on the severity of symptoms and the case fatality rate. Evidence Acquisition: A comprehensive literature search was …

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Gynecology

Joanna Davies, Rezan Abdul Kadir

The frequency and severity of gynecological bleeding have long been underestimated in women with inherited bleeding disorders (IBDs). Heavy menstrual bleeding (HMB) is the most common presenting symptom for women with IBD. Menstrual blood loss can be recorded with a high degree …

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Noninvasive detection of F8 int22h-related inversions and sequence variants in maternal plasma of hemophilia carriers

Irena Hudecova, Peiyong Jiang, Joanna Davies, Yuk Ming Dennis Lo et autres

Key Points Droplet digital PCR is an affordable and user-friendly method for the detection of F8 and F9 sequence variants in maternal plasma. Targeted MPS accurately determines fetal inheritance of F8 int22h-related inversions, using maternal plasma of pregnant hemophilia carriers.

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Heavy menstrual bleeding: An update on management

Joanna Davies, Rezan Abdul Kadir

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P-067: The obstetric management and outcome in carriers of haemophilia

André Luís Lacerda Bachi, Joanna Davies, Debra Pollard, T. T. Yee et autres

The Management of Factor XI Deficiency in Pregnancy

Joanna Davies, Rezan Abdul Kadir

Management of factor XI (FXI) deficiency in pregnancy is complicated by lack of correlation between FXI level and bleeding risk. Clinicians should be vigilant about the potential for prolonged or excessive bleeding following miscarriage or termination of pregnancy, or postpartum hemorrhage (PPH). …

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The role of rotational thromboelastometry in assessment of haemostasis during pregnancy in women with factor XI deficiency

Joanna Davies, Ann Harper, Rezan Abdul Kadir

Introduction Women with factor XI (FXI) deficiency are at an increased risk of bleeding complications at delivery. Obstetric management is complicated by a lack of correlation between FXI level and bleeding risk. Aim The aims of this study were to assess the …

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Mode of delivery and cranial bleeding in newborns with haemophilia: a systematic review and meta‐analysis of the literature

Joanna Davies, Rezan Abdul Kadir

OBJECTIVES: Cranial bleeding at birth can result in significant neurological morbidity in newborns with haemophilia. The optimum mode of delivery (MOD) of a potentially affected foetus remains controversial. AIM: The aim of this review is to ascertain overall incidence of cranial bleeding …

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PFM.18 UK variation in prenatal management of Congenital Adrenal Hyperplasia

CL Mercer, Michelle M. Coleman, Joanna Davies, DG Wellesley

Introduction Congenital adrenal hyperplasia (CAH) is a relatively common condition with a population carrier frequency of 1:50. Antenatal administration of dexamethasone treatment has been used to reduce virilisation in affected female offspring. There is however, considerable national/international variability regarding this treatment, including …

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The Effect Of Thrombotic Markers On The Severity Of Bleeding Symptoms In Women With Inherited Bleeding Disorders

Susan Halimeh, Joanna Davies, Rezan Abdul Kadir

Background Women with inherited bleeding disorders demonstrate heterogenicity in bleeding symptoms that do not always correlate to underlying clotting factor levels. This is problematic when predicting the bleeding risk, especially when haemostatic challenge is anticipated. The effect of thrombotic variables in reducing …

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Pregnancy complications and obstetric care in women with inherited bleeding disorders

Rezan Abdul Kadir, Joanna Davies, Rochelle Winikoff, Debra Pollard et autres

Women with inherited bleeding disorders (IBD) require the input of a multidisciplinary team to improve outcomes of pregnancy. The role of the haemophilia nurse within the multidisciplinary team is to provide educational and emotional support to the women and to facilitate and …

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